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Rap1a Overlaps the AGE/RAGE Signaling Cascade to Alter Expression of α-SMA, p-NF-κB, and p-PKC-ζ in Cardiac Fibroblasts Isolated from Type 2 Diabetic Mice

Cells(2021)10.3390/cells10030557Source: DataRank Database

Rap1a Overlaps the AGE/RAGE Signaling Cascade to Alter Expression of α-SMA, p-NF-κB, and p-PKC-ζ in Cardiac Fibroblasts Isolated from Type 2 Diabetic Mice is a research paper published in Cells (2021). On theSindex it has a DataRank of 0. It has been cited 28 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access28 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 2.21)OA: goldTopics (56)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

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Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (2)

James A. Stewart ORCID,Stephanie D. Burr ORCID

Live enrichment

PubMed:33806572 PMC:PMC8000763 OpenAlex:https://openalex.org/W3134123890

Congressionally Directed Medical Research Programs

Grant: 81XWH-16-1-0171

National Institutes of Health

Grant: R15HL129174

University of Mississippi

Grant: Department of BioMolecular Sciences

National Institutes of Health

Grant: 1R15HL129174-01A1

Rap1a mediates ECM remodeling by intersecting AGE/RAGE signaling in type II diabetes mellitus

FWCI

2.21

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/2073-4409/10/3/557/pdf

publisherhttps://www.mdpi.com/2073-4409/10/3/557/pdf

journalhttps://doi.org/10.3390/cells10030557

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33806572

repositoryhttps://doaj.org/article/675d1bba55e14455add46d6fdfa75f37

Fields of Study

Advanced Glycation End Products researchCardiovascular Function and Risk FactorsParkinson's Disease Mechanisms and Treatments0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsDiabetes Mellitus, ExperimentalDisease Models, AnimalFibroblastsMaleMiceNF-kappa BReceptor for Advanced Glycation End ProductsSignal Transductionrap1 GTP-Binding Proteins

MeSH Terms

Receptor for Advanced Glycation End ProductsAnimalsDiabetes Mellitus, ExperimentalDisease Models, AnimalFibroblastsMaleSignal TransductionNF-kappa Brap1 GTP-Binding ProteinsMice

Keywords

Rage (emotion)EndocrinologyInternal medicineInflammationOxidative stressMedicineDiabetic cardiomyopathyCell biologyBiologyHeart failureCardiomyopathyNeuroscienceHeartFibroblastsDiabetesMyofibroblastsRap1aAge/rageMaleQH573-671Receptor for Advanced Glycation End ProductsNF-kappa Brap1 GTP-Binding ProteinsArticleDiabetes Mellitus, ExperimentalDisease Models, AnimalMiceAnimalsCytologySignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of Exploring the mechanism by which aqueous Gynura divaricata inhibits diabetic foot based on network pharmacology, molecular docking and experimental verification

10.6084/m9.figshare.26563042.v1figshare

Additional file 1 of Exploring the mechanism by which aqueous Gynura divaricata inhibits diabetic foot based on network pharmacology, molecular docking and experimental verification

10.6084/m9.figshare.26563042figshare