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The HSP90 Inhibitor, AUY-922, Protects and Repairs Human Lung Microvascular Endothelial Cells from Hydrochloric Acid-Induced Endothelial Barrier Dysfunction

Cells(2021)10.3390/cells10061489Source: DataRank Database

The HSP90 Inhibitor, AUY-922, Protects and Repairs Human Lung Microvascular Endothelial Cells from Hydrochloric Acid-Induced Endothelial Barrier Dysfunction is a research paper published in Cells (2021). On theSindex it has a DataRank of 0. It has been cited 26 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access26 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 1.48)OA: goldTopics (64)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Pavel Solopov ORCID,Betsy Gregory,John D. Catravas ORCID,Ruben Manuel Luciano Colunga Biancatelli ORCID

Live enrichment

PubMed:34199261 PMC:PMC8232030 OpenAlex:https://openalex.org/W3166320912

NIEHS NIH HHS

Grant: U01 ES030674

NIH Office of the Director

Grant: UO1ES030674

National Institutes of Health

Grant: 1U01ES030674-01A1

Antidotes against HCI-induced chronic lung injury

FWCI

1.48

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/2073-4409/10/6/1489/pdf?version=1623580207

publisherhttps://www.mdpi.com/2073-4409/10/6/1489/pdf?version=1623580207

journalhttps://doi.org/10.3390/cells10061489

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34199261

repositoryhttps://digitalcommons.odu.edu/bioelectrics_pubs/310

Fields of Study

Heat shock proteins researchClimate Change and Health ImpactsSepsis Diagnosis and Treatment0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansHydrochloric AcidIsoxazolesLungResorcinolsRespiratory Distress SyndromeHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsMyosin Light ChainsrhoA GTP-Binding ProteinMAP Kinase Signaling SystemCardiac MyosinsEndothelial CellsMicrovessels

Keywords

RHOAProtein kinase BCell biologyEndothelial dysfunctionBarrier functionMyosin light-chain kinaseEndothelial stem cellCancer researchChemistryEndothelial activationEndotheliumBiologyPhosphorylationSignal transductionBiochemistryEndocrinologyHeat Shock proteinAcidosishydrochloric acidHClAcute Lung InjuryHsp90 InhibitionAuy-922Myosin Light ChainsBiomedicalPulmonologyMAP Kinase Signaling SystemRespiratory SystemCardiologyArticleHumansHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsLungHCIRespiratory Distress SyndromeQH573-671Endothelial CellsIsoxazolesResorcinolsMicrovesselsCytologyrhoA GTP-Binding ProteinCardiac Myosins

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being