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Generation of Isogenic hiPSCs with Targeted Edits at Multiple Intronic SNPs to Study the Effects of the Type 2 Diabetes Associated KCNQ1 Locus in American Indians

Cells(2022)10.3390/cells11091446Source: DataRank Database

Generation of Isogenic hiPSCs with Targeted Edits at Multiple Intronic SNPs to Study the Effects of the Type 2 Diabetes Associated KCNQ1 Locus in American Indians is a research paper published in Cells (2022). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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Enrichment:Funding (1 grants)Impact (FWCI 1.89)OA: goldTopics (34)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Michael Traurig,Jeff Sutherland ORCID,Yunhua L. Muller ORCID,Emma D. Grellinger,Lucas Saporito

Live enrichment

PubMed:35563754 PMC:PMC9102014 OpenAlex:https://openalex.org/W4224731118

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: Intramural

FWCI

1.89

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/2073-4409/11/9/1446/pdf?version=1651137653

publisherhttps://www.mdpi.com/2073-4409/11/9/1446/pdf?version=1651137653

publisherhttps://www.mdpi.com/2073-4409/11/9/1446/pdf

journalhttps://doi.org/10.3390/cells11091446

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35563754

Fields of Study

Pancreatic function and diabetesEpigenetics and DNA MethylationGenetic Syndromes and Imprinting

MeSH Terms

AdultDiabetes Mellitus, Type 2HumansGenomic ImprintingPolymorphism, Single NucleotideAmerican Indian or Alaska NativeKCNQ1 Potassium ChannelInduced Pluripotent Stem Cells

Keywords

BiologyLocus (genetics)GeneticsCRISPRInduced pluripotent stem cellSingle-nucleotide polymorphismGenomic imprintingGeneAlleleImprinting (psychology)Copy-number variationGenotypeGenomeDNA methylationGene expressionEmbryonic stem cellType 2 diabetesKCNQ1H19Cdkn1cHipscsAllele-specific Guide RnaPancreatic-beta Like Cells

Sustainable Development Goals

SDG 0: Good health and well-being

Generation of Isogenic hiPSCs with Targeted Edits at Multiple Intronic SNPs to Study the Effects of the Type 2 Diabetes Associated KCNQ1 Locus in American Indians

FAIR Checklist

Authors (9)

Funding (1 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)