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PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension

Cells(2023)10.3390/cells12020316Source: DataRank Database

PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension is a research paper published in Cells (2023). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Scored on demand from live citation data

Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 0.66)OA: goldTopics (47)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Xuefei Tian ORCID,Lan Zhao ORCID,Katharina Schimmel ORCID,Christopher J. Rhodes ORCID,Martin R. Wilkins ORCID

Live enrichment

PubMed:36672250 PMC:PMC9857213 OpenAlex:https://openalex.org/W4316466040

National Institutes of Health

Grant: R01 HL128734

National Institutes of Health

Grant: PR161256

NHLBI NIH HHS

Grant: T32 HL098049

NHLBI NIH HHS

Grant: R01 HL158714

British Heart Foundation

Grant: FS/SBSRF/22/31025

BLRD VA

Grant: I01 BX005628

National Institutes of Health

Grant: 1R01HL128734-01A1

Targeting Novel BMPR2 modifiers in Pulmonary Hypertension with Repurposed Drugs

FWCI

0.66

Citation Percentile

0.6%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/2073-4409/12/2/316/pdf?version=1673842840

publisherhttps://www.mdpi.com/2073-4409/12/2/316/pdf?version=1673842840

publisherhttps://www.mdpi.com/2073-4409/12/2/316/pdf

journalhttps://doi.org/10.3390/cells12020316

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36672250

Fields of Study

Protein Tyrosine PhosphatasesPulmonary Hypertension Research and TreatmentsGalectins and Cancer Biology0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Pulmonary Arterial HypertensionAnimalsHumansHypertension, PulmonaryPulmonary ArteryVascular DiseasesRNA, Small InterferingEndothelial CellsMiceBone Morphogenetic Protein Receptors, Type IIProtein Tyrosine Phosphatase, Non-Receptor Type 1

Keywords

BMPR2Downregulation and upregulationSignal transductionProtein tyrosine phosphataseCell biologyCancer researchBiologyChemistryBone morphogenetic proteinBiochemistryGeneHypoxiaPulmonary hypertensionendothelial dysfunctionPtpn1Bmpr2 SignalingProtein Tyrosine Phosphatase, Non-Receptor Type 1Pulmonary Arterial HypertensionQH573-671Hypertension, PulmonaryEndothelial CellsPulmonary ArteryBone Morphogenetic Protein Receptors, Type IIArticleMiceAnimalsHumansVascular DiseasesRNA, Small InterferingCytology

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being