Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Dual Inhibition of Phosphodiesterase 3 and 4 Enzymes by Ensifentrine Protects against MRSA-Induced Lung Endothelial and Epithelial Dysfunction

Cells(2024)10.3390/cells13211750Source: DataRank Database

Dual Inhibition of Phosphodiesterase 3 and 4 Enzymes by Ensifentrine Protects against MRSA-Induced Lung Endothelial and Epithelial Dysfunction is a research paper published in Cells (2024). On theSindex it has a DataRank of 0. It has been cited 6 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

Download PDF

Cite:

Linked data & code

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.96)OA: goldTopics (60)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (4)

Lucille N. Meliton,Steven M. Dudek ORCID,Eleftheria Letsiou ORCID,Mohammed Yaman Al Matni

Live enrichment

PubMed:39513857 PMC:PMC11545647 OpenAlex:https://openalex.org/W4403691210

American Heart Association

Grant: 932176/EL/2022

American Heart Association

Grant: R01 HL167518

National Institutes of Health

Grant: 5R01HL167518-02

Pathobiology of MRSA-induced Endothelial Permeability and Acute Lung Injury

FWCI

0.96

Citation Percentile

0.7%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.3390/cells13211750

publisherhttps://doi.org/10.3390/cells13211750

publisherhttps://www.mdpi.com/2073-4409/13/21/1750/pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39513857

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11545647

Fields of Study

Phosphodiesterase function and regulationNitric Oxide and Endothelin EffectsHeart Failure Treatment and Management03 medical and health sciences0303 health sciences

MeSH Terms

A549 CellsCarbolinesEpithelial CellsHumansIsoquinolinesLungPyrimidinonesCadherinsVascular Cell Adhesion Molecule-1Protective AgentsEndothelial CellsBenzophenanthridinesCyclic Nucleotide Phosphodiesterases, Type 3Cyclic Nucleotide Phosphodiesterases, Type 4Methicillin-Resistant Staphylococcus aureusPhosphodiesterase 3 InhibitorsPhosphodiesterase 4 Inhibitors

Keywords

PhosphodiesteraseEnzymeChemistryPharmacologyEndothelial dysfunctionMedicineBiochemistryInternal medicineInflammationPermeabilityARDSendothelialAcute Lung InjuryAlveolar EpitheliumRpl554EnsifentrinePulmonary and Respiratory MedicineMethicillin-Resistant Staphylococcus aureusVascular Cell Adhesion Molecule-1Medicine and PharmacologyPyrimidinonesPhosphodiesterase 3 InhibitorsProtective AgentsArticleHumansLungBenzophenanthridinesQH573-671Endothelial CellsEpithelial CellsCadherinsIsoquinolinesCyclic Nucleotide Phosphodiesterases, Type 3Cyclic Nucleotide Phosphodiesterases, Type 4A549 CellsPhosphodiesterase 4 InhibitorsCytologyCarbolines

Sustainable Development Goals

SDG 0: Good health and well-being

Supplemental data for https://doi.org/10.3390/cells13211750

10.6084/m9.figshare.28640228.v1figshare

Supplemental data for https://doi.org/10.3390/cells13211750

10.6084/m9.figshare.28640228figshare