🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Downregulated ALDH2 Contributes to Tumor Progression and Targeted Therapy Resistance in Human Metastatic Melanoma Cells

Cells(2025)10.3390/cells14120913Source: DataRank Database

Downregulated ALDH2 Contributes to Tumor Progression and Targeted Therapy Resistance in Human Metastatic Melanoma Cells is a research paper published in Cells (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (13 grants)OA: goldTopics (52)IDs (PubMed)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (8)

Takeshi Yamauchi ORCID,Karenna Sandoval,Kira Villarreal,Man Wai Charlotte Kwong,Emily J. Swanson

Live enrichment

PubMed:40558540

Veterans Affairs Merit Review Award

Grant: 5I01BX001228

Veterans Affairs Merit Review Award

Grant: R01CA197919

Veterans Affairs Merit Review Award

Grant: R01AI156534

Veterans Affairs Merit Review Award

Grant: R21AA028904

Veterans Affairs Merit Review Award

Grant: P30AR057212

National Institutes of Health

Grant: 5R01CA197919-05

Modulation of inflammasome-mediated cytokine activation by EGCG in human melanoma.

National Institutes of Health

Grant: 5I01BX001228-03

Autoinflammation in Human Melanoma

National Institutes of Health

Grant: 5P30AR057212-03

Molecular Analysis, Modeling and Correction of Skin Diseases

National Institutes of Health

Grant: 5R01AI156534-02

The role of IL-37 in human regulatory T cells

National Institutes of Health

Grant: 1R21AA028904-01A1

Ethanol-induced skin changes

BLRD VA

Grant: I01 BX006598

BLRD VA

Grant: I01 BX001228

NIH/NIAID

Grant: R01AI156534-01A1

goldLicense: cc-by

publisherhttps://www.mdpi.com/2073-4409/14/12/913/pdf?version=1750145775

publisherhttps://www.mdpi.com/2073-4409/14/12/913/pdf

repositoryhttps://doaj.org/article/38f05fb361434c9aac7a4d83d0f4ec07

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12191128

https://doi.org/10.3390/cells14120913

Fields of Study

03 medical and health sciences0302 clinical medicineHumansMelanomaAldehyde Dehydrogenase, MitochondrialDown-RegulationCell Line, TumorDrug Resistance, NeoplasmDisease ProgressionAnimalsNeoplasm MetastasisGene Expression Regulation, NeoplasticMiceMAP Kinase Signaling SystemCell ProliferationMolecular Targeted Therapy

MeSH Terms

HumansMelanomaAldehyde Dehydrogenase, MitochondrialDown-RegulationCell Line, TumorDrug Resistance, NeoplasmDisease ProgressionAnimalsNeoplasm MetastasisGene Expression Regulation, NeoplasticMiceMAP Kinase Signaling SystemCell ProliferationMolecular Targeted Therapy

Keywords

drug resistanceQH573-671MAP Kinase Signaling SystemAldehyde Dehydrogenase, MitochondrialDown-Regulationtargeted therapyArticleGene Expression Regulation, NeoplasticMiceDrug Resistance, NeoplasmCell Line, TumormelanomaDisease ProgressionHumansAnimalsMolecular Targeted Therapyaldehyde dehydrogenase 2Neoplasm MetastasisMAPK/ERKCytologyacetaldehydeCell Proliferation