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HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1

Cells(2020)10.3390/cells9102237Source: DataRank Database

HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1 is a research paper published in Cells (2020). On theSindex it has a DataRank of 0. It has been cited 25 times.

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Open Access25 citations

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Enrichment:Funding (4 grants)Impact (FWCI 0.97)OA: goldTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Mu Zhang,Jheng-Yu Wu,Hu Chen ORCID,Shengyan Xiang ORCID,Xinran Geng ORCID

Live enrichment

PubMed:33020410 PMC:PMC7600810 OpenAlex:https://openalex.org/W3091346660

National Institutes of Health

Grant: R01 CA164147-01

NCI NIH HHS

Grant: T32 CA009531

NCI NIH HHS

Grant: R01 CA164147

National Institutes of Health

Grant: 5R01CA164147-04

Role of HDAC6 in platinum resistance of non-small cell lung cancer

FWCI

0.97

Citation Percentile

0.7%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/2073-4409/9/10/2237/pdf?version=1601802873

publisherhttps://www.mdpi.com/2073-4409/9/10/2237/pdf?version=1601802873

publisherhttps://www.mdpi.com/2073-4409/9/10/2237/pdf

journalhttps://doi.org/10.3390/cells9102237

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33020410

Fields of Study

Histone Deacetylase Inhibitors ResearchUbiquitin and proteasome pathwaysEpigenetics and DNA Methylation0301 basic medicine03 medical and health sciences

MeSH Terms

Checkpoint Kinase 1Histone Deacetylase 6AnimalsCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsRadiation ToleranceTransfectionMice, KnockoutMice

Keywords

Ubiquitin ligaseGene knockdownRadiosensitivityCell biologyCell cycleDNA damageChemistryCHEK1DNA ligaseDNA repairCell cycle checkpointCancer researchUbiquitinBiologyCellBiochemistryDNAApoptosisMedicineRadiation therapyUbiquitinationHistone Deacetylase 6 (Hdac6)Dna Damage Response (Ddr)Ionizing Radiation (Ir)Ubiquitin E3 LigaseCheckpoint Kinase 1 (Chk1)Mice, KnockoutLung NeoplasmsQH573-671Histone Deacetylase 6TransfectionRadiation ToleranceArticleMiceCarcinoma, Non-Small-Cell LungCheckpoint Kinase 1AnimalsHumansCytology

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1

FAIR Checklist

Authors (11)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)