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The Genetic Architecture of a Congenital Heart Defect Is Related to Its Fitness Cost

Genes(2021)10.3390/genes12091368Source: DataRank Database

The Genetic Architecture of a Congenital Heart Defect Is Related to Its Fitness Cost is a research paper published in Genes (2021). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.15)OA: goldTopics (48)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Suk D. Regmi,Rachel A. Magnan,Nelson Ugwu ORCID,Yidan Qin ORCID,Claire E. Schulkey ORCID

Live enrichment

PubMed:34573350 OpenAlex:https://openalex.org/W3198447769

National Institutes of Health

Grant: T32 HL007873

National Institutes of Health

Grant: F30 HL136077

National Institutes of Health

Grant: R01 HL105857

American Heart Association

Grant: Established Investigator Award

FWCI

0.15

Citation Percentile

0.5%

Citation Trend

2022

2024

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/2073-4425/12/9/1368/pdf?version=1630401297

publisherhttps://www.mdpi.com/2073-4425/12/9/1368/pdf?version=1630401297

publisherhttps://www.mdpi.com/2073-4425/12/9/1368/pdf

journalhttps://doi.org/10.3390/genes12091368

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34573350

Fields of Study

Congenital heart defects researchChromosomal and Genetic VariationsRNA and protein synthesis mechanismsAnimalsAnimals, NewbornDisease Models, AnimalFemaleGenetic FitnessGenetic LociHeart Septal DefectsHeart Septal Defects, AtrialHeart Septal Defects, VentricularHomeobox Protein Nkx-2.5HumansMaleMiceMice, TransgenicSeverity of Illness IndexAtrioventricular Septal Defect

MeSH Terms

Homeobox Protein Nkx-2.5AnimalsAnimals, NewbornDisease Models, AnimalFemaleHeart Septal DefectsHeart Septal Defects, AtrialHeart Septal Defects, VentricularHumansMaleMice, TransgenicSeverity of Illness IndexMiceGenetic FitnessGenetic Loci

Keywords

EpistasisGenetic architectureBiologyGeneticsPhenotypeHeart diseaseInbred strainGeneInternal medicineMedicinecongenital heart defectsgenetic epistasismodifier genesquantitative trait loci

Sustainable Development Goals

SDG 0: Good health and well-being