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FGF21 Protects against Aggravated Blood-Brain Barrier Disruption after Ischemic Focal Stroke in Diabetic db/db Male Mice via Cerebrovascular PPARγ Activation

International Journal of Molecular Sciences(2020)10.3390/ijms21030824Source: DataRank Database

FGF21 Protects against Aggravated Blood-Brain Barrier Disruption after Ischemic Focal Stroke in Diabetic db/db Male Mice via Cerebrovascular PPARγ Activation is a research paper published in International Journal of Molecular Sciences (2020). On theSindex it has a DataRank of 0. It has been cited 69 times.

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Open Access69 citations

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Enrichment:Funding (2 grants)OA: goldTopics (42)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Reusable (0/3)

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Authors (10)

Li Lin ORCID,Ning Liu ORCID,Qingzhi Wang ORCID,Jing Yuan ORCID,Yadan Li ORCID

Live enrichment

PubMed:32012810 PMC:PMC7037567

National Institutes of Health

Grant: R01 NS099539

National Institutes of Health

Grant: 7R01NS099539-05

Recombinant FGF21 as a novel approach for treating ischemic stroke in type 2 diabetes

goldLicense: cc-by

publisherhttps://www.mdpi.com/1422-0067/21/3/824/pdf?version=1580390595

publisherhttps://www.mdpi.com/1422-0067/21/3/824/pdf

repositoryhttps://doaj.org/article/143f743f8a484619b6e29d81409a1150

repositoryhttp://dx.doi.org/10.3390/ijms21030824

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7037567

Fields of Study

0301 basic medicine03 medical and health sciences0302 clinical medicine

MeSH Terms

Blood-Brain BarrierCells, CulturedEndothelial CellsAnimalsHumansMiceDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Fibroblast Growth FactorsPPAR gammaRecombinant ProteinsGene Expression RegulationMaleStrokePrimary Cell CultureTight Junction Proteins

Keywords

Type 2 diabetesDb/db MouseHuman Brain Microvascular Endothelial CellFibroblast Growth Factor 21Focal Ischemic StrokeBlood—brain BarrierMalePrimary Cell CultureArticleDiabetes Mellitus, ExperimentalMiceAnimalsHumansCells, CulturedTight Junction ProteinsEndothelial CellsRecombinant ProteinsFibroblast Growth FactorsPPAR gammaStrokeDiabetes Mellitus, Type 2Gene Expression RegulationBlood-Brain Barrier

Sustainable Development Goals

SDG 3: 3. Good health

FGF21 Protects against Aggravated Blood-Brain Barrier Disruption after Ischemic Focal Stroke in Diabetic db/db Male Mice via Cerebrovascular PPARγ Activation

FAIR Checklist

Authors (10)

Funding (2 grants)

Open Access

Topics

Annotations (Europe PMC)