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Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization

International Journal of Molecular Sciences(2020)10.3390/ijms21072614Source: DataRank Database

Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization is a research paper published in International Journal of Molecular Sciences (2020). On theSindex it has a DataRank of 0. It has been cited 154 times.

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Open Access154 citations

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Enrichment:Funding (18 grants)Impact (FWCI 7.52)OA: goldTopics (77)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Kristýna Krasulová ORCID,Petra Pečinková,Adéla Marcalíková,Radim Vrzal ORCID,Lenka Zemánková ORCID

Live enrichment

PubMed:32283770 PMC:PMC7177849 OpenAlex:https://openalex.org/W3015365786

Grantová Agentura České Republiky

Grant: 20-00449S

Univerzita Palackého v Olomouci

Grant: PrF-2020-006

Akademie Věd České Republiky

Grant: RVO 68081707

National Institutes of Health

Grant: P30CA013330

National Institutes of Health

Grant: P30DK020541

National Institutes of Health

Grant: CA127231

National Institutes of Health

Grant: CA161879

U.S. Department of Defense

Grant: PR160167

U.S. Department of Defense

Grant: R43DK105694

U.S. Department of Defense

Grant: P30DK041296

Crohn's and Colitis Foundation of America

Grant: 362520

National Institutes of Health

Grant: 2P30DK041296-16

Liver Pathobiology and Gene Therapy Research Core Center

National Institutes of Health

Grant: 5P30DK020541-46

Einstein-Mount Sinai Diabetes Research Center

National Institutes of Health

Grant: 1R43DK105694-01

Pregnane X Receptor (PXR) Antagonists for Non-Alcoholic Fatty Liver Disease

National Institutes of Health

Grant: 5R01CA161879-06

Development of Novel Drugs to Alleviate CPT-11 Toxicity

National Institutes of Health

Grant: 5R01CA127231-03

Chemical Modulation of Orphan Nuclear Receptor Function

National Institutes of Health

Grant: 3P30CA013330-39S3

Core Support for Cancer Center

National Institutes of Health

Grant: 5R01CA222469-06

Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer

FWCI

7.52

Citation Percentile

1.0%

Influential Citations

Citation Trend

2020

2021

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2023

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2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/21/7/2614/pdf?version=1586434406

GOLDhttps://www.mdpi.com/1422-0067/21/7/2614/pdf?version=1586434406

publisherhttps://www.mdpi.com/1422-0067/21/7/2614/pdf?version=1586434406

publisherhttps://www.mdpi.com/1422-0067/21/7/2614/pdf

journalhttps://doi.org/10.3390/ijms21072614

Fields of Study

Toxic Organic Pollutants ImpactPharmacogenetics and Drug MetabolismEffects and risks of endocrine disrupting chemicalsChemistryMedicineBiologyEnvironmental Science0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsBasic Helix-Loop-Helix ProteinsCell Line, TumorCytochrome P-450 CYP1A1Gastrointestinal MicrobiomeGene ExpressionGenes, ReporterHumansIndolesLigandsMetabolic Networks and PathwaysMicePromoter Regions, GeneticProtein BindingProtein MultimerizationReceptors, Aryl HydrocarbonTryptophan

MeSH Terms

Gastrointestinal MicrobiomeAnimalsHumansIndolesLigandsPromoter Regions, GeneticProtein BindingTryptophanGene ExpressionGenes, ReporterReceptors, Aryl HydrocarbonCytochrome P-450 CYP1A1Cell Line, TumorMiceBasic Helix-Loop-Helix ProteinsBasic Helix-Loop-Helix Transcription FactorsMetabolic Networks and PathwaysProtein Multimerization

Keywords

Aryl hydrocarbon receptorSkatoleTryptamineChemistryBiochemistryAcetamideTryptophanIndole testKynurenineTranscription factorGeneAmino acidOrganic chemistryIndolesMicrobiomeBasic Helix-Loop-Helix ProteinsGene ExpressionLigandsArticleMiceGenes, ReporterCell Line, TumorCytochrome P-450 CYP1A1AnimalsHumansPromoter Regions, GeneticGastrointestinal MicrobiomeReceptors, Aryl HydrocarbonBiochemistry and molecular biologyProtein MultimerizationMetabolic Networks and PathwaysProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 13: 13. Climate action

Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization

FAIR Checklist

Authors (12)

Funding (18 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)