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P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice

International Journal of Molecular Sciences(2021)10.3390/ijms22115528Source: DataRank Database

P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice is a research paper published in International Journal of Molecular Sciences (2021). On theSindex it has a DataRank of 0. It has been cited 37 times.

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Open Access37 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)Impact (FWCI 3.85)OA: goldTopics (81)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Eun Jung Park ORCID,Jihyun Je,Kyuho Jeong ORCID,Seung Pil Yun ORCID,Hye Jung Kim ORCID

Live enrichment

PubMed:34073834 PMC:PMC8197197 OpenAlex:https://openalex.org/W3165516254

National Research Foundation of Korea

Grant: 2015R1A5A2008833

National Research Foundation of Korea

Grant: 2017R1A2B4009387

FWCI

3.85

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/22/11/5528/pdf?version=1621999935

publisherhttps://www.mdpi.com/1422-0067/22/11/5528/pdf?version=1621999935

publisherhttps://www.mdpi.com/1422-0067/22/11/5528/pdf

journalhttps://doi.org/10.3390/ijms22115528

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34073834

Fields of Study

Liver Disease Diagnosis and TreatmentMetabolism, Diabetes, and CancerAdipose Tissue and MetabolismAMP-Activated Protein KinasesAcetyl-CoA CarboxylaseAlanine TransaminaseAnimalsAspartate AminotransferasesBody WeightCD36 AntigensCarnitine O-PalmitoyltransferaseDiet, High-FatFatty Acid SynthasesFatty AcidsInsulinInsulin ResistanceLipaseLipogenesisMaleMiceMice, Inbred C57BLMice, KnockoutMice, ObeseMitochondriaNon-alcoholic Fatty Liver DiseaseObesityPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaReceptors, Purinergic P2Y2Stearoyl-CoA DesaturaseAcyltransferases

MeSH Terms

Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaAcetyl-CoA CarboxylaseAcyltransferasesAlanine TransaminaseAnimalsAspartate AminotransferasesBody WeightCarnitine O-PalmitoyltransferaseFatty AcidsInsulinInsulin ResistanceLipaseMaleMice, Inbred C57BLMice, ObeseMitochondriaObesityStearoyl-CoA DesaturaseMice, KnockoutCD36 AntigensLipogenesisMiceAMP-Activated Protein KinasesReceptors, Purinergic P2Y2Diet, High-FatFatty Acid SynthasesNon-alcoholic Fatty Liver Disease

Keywords

EndocrinologyInternal medicineLipogenesisFatty liverSteatosisInsulin resistanceFatty acid synthaseCD36Beta oxidationBiologyCarnitineAMPKLipid metabolismInsulinProtein kinase AMedicineBiochemistryKinaseMetabolismReceptorfatty acid β-oxidationhepatic steatosisNafldP2y2r

Sustainable Development Goals

SDG 0: Good health and well-being