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Proteotoxic Stress as an Exploitable Vulnerability in Cells with Hyperactive AKT

International Journal of Molecular Sciences(2021)10.3390/ijms222111376Source: DataRank Database

Proteotoxic Stress as an Exploitable Vulnerability in Cells with Hyperactive AKT is a research paper published in International Journal of Molecular Sciences (2021). On theSindex it has a DataRank of 0. It has been cited 10 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access10 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 0.50)OA: goldTopics (45)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Lorin Brown,Hannah Slabodkin ORCID,Julia V. Kichina,Eugene Kandel ORCID,Mahamat Babagana

Live enrichment

PubMed:34768807 PMC:PMC8583472 OpenAlex:https://openalex.org/W3205683686

National Institutes of Health

Grant: K01CA098176

National Institutes of Health

Grant: R21CA137708

National Institutes of Health

Grant: P30CA16056

Roswell Park Alliance Foundation, Roswell Park Cancer Institute

Grant: NA

National Institutes of Health

Grant: 5K01CA098176-02

Genetic Determinants of Akt-induced Transformation

National Institutes of Health

Grant: 3R21CA137708-03S1

Array-Assisted Insertional Mutagenesis for Molecular Analysis of Cancer

National Institutes of Health

Grant: 5P30CA016056-40

Roswell Park Cancer Institute Cancer Center Support Grant

FWCI

0.50

Citation Percentile

0.6%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/22/21/11376/pdf?version=1634868208

publisherhttps://www.mdpi.com/1422-0067/22/21/11376/pdf?version=1634868208

publisherhttps://www.mdpi.com/1422-0067/22/21/11376/pdf

journalhttps://doi.org/10.3390/ijms222111376

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34768807

Fields of Study

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins researchPI3K/AKT/mTOR signaling in cancer0301 basic medicine03 medical and health sciences

MeSH Terms

X-Box Binding Protein 1Heat Shock Transcription FactorsAnimalsCells, CulturedGene Expression RegulationHumansStress, PhysiologicalHeat-Shock ResponseProto-Oncogene Proteins c-aktMiceHEK293 CellsProteolysis

Keywords

Protein kinase BPTENPI3K/AKT/mTOR pathwayHSF1Cell biologyBiologyCancer researchHeat shock proteinSignal transductionHsp70GeneticsHeat shockHSP90AKTXbp1X-Box Binding Protein 1ArticleMiceHEK293 CellsGene Expression RegulationHeat Shock Transcription FactorsStress, PhysiologicalProteolysisAnimalsHumansProto-Oncogene Proteins c-aktCells, CulturedHeat-Shock Response

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: No poverty