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New Oxazolo[5,4-d]pyrimidines as Potential Anticancer Agents: Their Design, Synthesis, and In Vitro Biological Activity Research

International Journal of Molecular Sciences(2022)10.3390/ijms231911694Source: DataRank Database

New Oxazolo[5,4-d]pyrimidines as Potential Anticancer Agents: Their Design, Synthesis, and In Vitro Biological Activity Research is a research paper published in International Journal of Molecular Sciences (2022). On theSindex it has a DataRank of 0. It has been cited 19 times.

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Open Access19 citations

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Enrichment:Funding (3 grants)OA: goldTopics (51)IDs (PubMed, PMC)Annotations (2)SDGs (1)

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Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Marcin Mą̨czyński ORCID,Żaneta Czyżnikowska ORCID,Benita Wiatrak ORCID,Izabela Jęśkowiak ORCID,A. Czerski

Live enrichment

PubMed:36232997 PMC:PMC9569971

Wroclaw Medical University

Grant: SUBK.D090.22.051

Wroclaw Medical University

Grant: 305

National Institutes of Health

Grant: 5P41GM103311-36

Resource for Biocomputing Visualization and Informatics

goldLicense: cc-by

publisherhttps://www.mdpi.com/1422-0067/23/19/11694/pdf?version=1665369013

publisherhttps://www.mdpi.com/1422-0067/23/19/11694/pdf

repositoryhttps://dx.doi.org/10.3390/ijms231911694

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9569971

Europe_PMChttps://europepmc.org/articles/PMC9569971

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansAdenocarcinomaColonic NeoplasmsCisplatinIsoxazolesPyrimidinesFluorouracilPurinesVascular Endothelial Growth Factor Receptor-2Vascular Endothelial Growth Factor AAntineoplastic AgentsDrug Screening Assays, AntitumorCell ProliferationMolecular StructureStructure-Activity RelationshipDose-Response Relationship, DrugMolecular Docking SimulationATP Binding Cassette Transporter, Subfamily B

Keywords

CytotoxicityMolecular dockingAnticancer activityAntimetabolitesIsoxazoleVegfr-2 InhibitorsOxazolo[5,4-d]pyrimidinesVascular Endothelial Growth Factor Aoxazolo[5; 4-d]pyrimidines; isoxazole; molecular docking; anticancer activity; cytotoxicity; antimetabolites; VEGFR-2 inhibitorsATP Binding Cassette Transporter, Subfamily Boxazolo[5Antineoplastic AgentsAdenocarcinomaArticleStructure-Activity Relationship4-d]pyrimidines; isoxazole; molecular docking; anticancer activity; cytotoxicity; antimetabolites; VEGFR-2 inhibitorsHumansCell ProliferationDose-Response Relationship, DrugMolecular Structureoxazolo[5,4-<i>d</i>]pyrimidinesIsoxazolesVascular Endothelial Growth Factor Receptor-2Molecular Docking SimulationPyrimidinesPurinesColonic NeoplasmsFluorouracilCisplatinDrug Screening Assays, Antitumor

Sustainable Development Goals

SDG 3: 3. Good health

New Oxazolo[5,4-d]pyrimidines as Potential Anticancer Agents: Their Design, Synthesis, and In Vitro Biological Activity Research

FAIR Checklist

Authors (7)

Funding (3 grants)

Open Access

Topics

Annotations (Europe PMC)