Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Next Generation Therapeutic Strategy for Treatment and Prevention of Alzheimer’s Disease and Aging-Associated Cognitive Decline: Transient, Once-in-a-Lifetime-Only Depletion of Intraneuronal Aβ (iAβ) by Its Targeted Degradation via Augmentation of Intra-iAβ-Cleaving Activities of BACE1 and/or BACE2

International Journal of Molecular Sciences(2023)10.3390/ijms242417586Source: DataRank Database

Next Generation Therapeutic Strategy for Treatment and Prevention of Alzheimer’s Disease and Aging-Associated Cognitive Decline: Transient, Once-in-a-Lifetime-Only Depletion of Intraneuronal Aβ (iAβ) by Its Targeted Degradation via Augmentation of Intra-iAβ-Cleaving Activities of BACE1 and/or BACE2 is a research paper published in International Journal of Molecular Sciences (2023). On theSindex it has a DataRank of 0. It has been cited 12 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

Download PDF

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)OA: goldTopics (35)IDs (PubMed)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (2)

Sophia Rits‐Volloch ORCID,Vladimir Volloch

Live enrichment

PubMed:38139415

NIH

Grant: RO1 AR036819

NIH

Grant: R21 GM056179

National Institutes of Health

Grant: 1R21GM056179-01

GLOBIN MRNA HYPERPRODUCTION IN RESPONSE TO ANEMIA

NIAMS NIH HHS

Grant: R01 AR036819

goldLicense: cc-by

publisherhttps://www.mdpi.com/1422-0067/24/24/17586/pdf?version=1702872817

publisherhttps://www.mdpi.com/1422-0067/24/24/17586/pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10744314/pdf/ijms-24-17586.pdf

https://doi.org/10.3390/ijms242417586

https://pubmed.ncbi.nlm.nih.gov/38139415

Fields of Study

03 medical and health sciences0302 clinical medicineHumansAlzheimer DiseaseAmyloid Precursor Protein SecretasesAspartic Acid EndopeptidasesAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAgingCognitive Dysfunction

MeSH Terms

HumansAlzheimer DiseaseAmyloid Precursor Protein SecretasesAspartic Acid EndopeptidasesAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAgingCognitive Dysfunction

Keywords

Amyloid beta-Protein PrecursorAgingAmyloid beta-PeptidesAlzheimer DiseasePerspectiveHumansAspartic Acid EndopeptidasesCognitive DysfunctionAmyloid Precursor Protein SecretasesACH2.0-based drugsAging-Associated Cognitive Decline (AACD)Alzheimer’s disease (AD)Amyloid Cascade Hypothesis 2.0 (ACH2.0)Aβ protein precursor (AβPP)AβPP-independent iAβ production pathwayBACE1/BACE2 activatorsintraneuronal Aβ (iAβ)

Sustainable Development Goals

SDG 3: 3. Good health