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Anti-Inflammatory and Antioxidant Pyrrolo[3,4-d]pyridazinone Derivatives Interact with DNA and Bind to Plasma Proteins—Spectroscopic and In Silico Studies

International Journal of Molecular Sciences(2024)10.3390/ijms25031784Source: DataRank Database

Anti-Inflammatory and Antioxidant Pyrrolo[3,4-d]pyridazinone Derivatives Interact with DNA and Bind to Plasma Proteins—Spectroscopic and In Silico Studies is a research paper published in International Journal of Molecular Sciences (2024). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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Enrichment:Funding (3 grants)Impact (FWCI 0.55)OA: goldTopics (44)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Edward Krzyżak ORCID,Julia Żądło,Maja Witczak,Łukasz Szczukowski ORCID,Jakub Mucha

Live enrichment

PubMed:38339061 PMC:PMC10855066 OpenAlex:https://openalex.org/W4391433962

Wroclaw Medical University

Grant: SUBZ.D290.24.041

NIGMS NIH HHS

Grant: R01 GM129325

National Institutes of Health

Grant: 5R01GM129325-08

ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale Modeling

FWCI

0.55

Citation Percentile

0.6%

Citation Trend

2024

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/25/3/1784/pdf?version=1706781269

publisherhttps://www.mdpi.com/1422-0067/25/3/1784/pdf?version=1706781269

publisherhttps://www.mdpi.com/1422-0067/25/3/1784/pdf

journalhttps://doi.org/10.3390/ijms25031784

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38339061

Fields of Study

Synthesis and Reactivity of HeterocyclesSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds01 natural sciences0104 chemical sciencesAntioxidantsAnti-Inflammatory AgentsDNAModels, MolecularBlood ProteinsMolecular Docking Simulation

MeSH Terms

Anti-Inflammatory AgentsAntioxidantsBlood ProteinsDNAModels, MolecularMolecular Docking Simulation

Keywords

ChemistryIn silicoOrosomucoidBiomoleculeDNAAntioxidantMoleculeBiochemistryBlood proteinsSmall moleculeAlbuminCombinatorial chemistryStereochemistryGlycoproteinOrganic chemistryGeneMolecular modellingFluorescence spectroscopyCd SpectroscopyPlasma ProteinsPyridazinone DerivativesModels, MolecularAnti-Inflammatory AgentsArticleAntioxidantsCD spectroscopy; DNA; fluorescence spectroscopy; molecular modelling; plasma proteins; pyridazinone derivativesMolecular Docking Simulation

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Clean water and sanitation

Anti-Inflammatory and Antioxidant Pyrrolo[3,4-d]pyridazinone Derivatives Interact with DNA and Bind to Plasma Proteins—Spectroscopic and In Silico Studies

FAIR Checklist

Authors (8)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)