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HSP70 Is a Critical Regulator of HSP90 Inhibitor’s Effectiveness in Preventing HCl-Induced Chronic Lung Injury and Pulmonary Fibrosis

International Journal of Molecular Sciences(2024)10.3390/ijms25031920Source: DataRank Database

HSP70 Is a Critical Regulator of HSP90 Inhibitor’s Effectiveness in Preventing HCl-Induced Chronic Lung Injury and Pulmonary Fibrosis is a research paper published in International Journal of Molecular Sciences (2024). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: goldTopics (68)IDs (PubMed, PMC)SDGs (1)

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Open Access

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Authors (7)

Pavel Solopov ORCID,Tierney Day,Betsy Gregory,Michael Osei-nkansah,Christiana Dimitropoulou

Live enrichment

PubMed:38339194 PMC:PMC10856755

CounterACT Program

Grant: UO1ES030674

NIEHS NIH HHS

Grant: U01 ES030674

National Institutes of Health

Grant: 1U01ES030674-01A1

Antidotes against HCI-induced chronic lung injury

CounterACT Program

National Institutes of Health Office of the Director (NIH OD)

goldLicense: cc-by

publisherhttps://www.mdpi.com/1422-0067/25/3/1920/pdf?version=1707121953

publisherhttps://www.mdpi.com/1422-0067/25/3/1920/pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10856755/pdf/ijms-25-01920.pdf

repositoryhttps://digitalcommons.odu.edu/bioelectrics_pubs/366

Europe_PMChttps://europepmc.org/articles/PMC10856755

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Endothelial CellsAnimalsHumansMicePulmonary FibrosisHydrochloric AcidBenzamidesPyrazolesAntineoplastic AgentsHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsLung InjuryGefitinib

Keywords

Heat shock proteinsHSP70Pulmonary fibrosishydrochloric acidGefitinibHsp90 InhibitorsChronic Lung InjuryTas-116Geranylgeranyl AcetoneRespiratory SystemApoptosisHydrochloric acid - toxicityChronic illnessesHSP90 heat-shock proteins - metabolismMiceChlorine gasPhosphorylationAmino AcidsLung injury - chemically inducedand ProteinsShockAntineoplastic agents - adverse effectsLung InjuryEndothelial cells - metabolismTransforming growth factorsBenzamidesCollagenGrowth factorsHSP70 heat-shock proteins - metabolismPulmonary fibrosis - metabolismKinasesAntineoplastic AgentsGefitinib - adverse effectsTherapeuticsLung injury - drug therapyArticleDrug approvalHumansAnimalsHSP70 Heat-Shock ProteinsHSP90 Heat-Shock ProteinsInflammationIndex medicusToxicityEndothelial CellsGrowth factor betaEthylenediaminetetraacetic acidPyrazolesLungsHealth aspectsPeptidesPulmonary fibrosis - chemically induced

Sustainable Development Goals

SDG 3: 3. Good health