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Structural Models for a Series of Allosteric Inhibitors of IGF1R Kinase

International Journal of Molecular Sciences(2024)10.3390/ijms25105368Source: DataRank Database

Structural Models for a Series of Allosteric Inhibitors of IGF1R Kinase is a research paper published in International Journal of Molecular Sciences (2024). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 1.51)OA: goldTopics (55)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Harish Vashisth ORCID,Jyoti Verma ORCID

Live enrichment

PubMed:38791406 PMC:PMC11121299 OpenAlex:https://openalex.org/W4396890739

National Institutes of Health

Grant: R35GM138217

National Institutes of Health

Grant: P20GM113131

NIH HHS

Grant: R35GM138217 and P20GM113131

National Institutes of Health

Grant: 3P20GM113131-05S2

Targeting STAT3 in Ovarian Cancer- Center for Integrated Biomedical and Bioengineering (CIBBR)

National Institutes of Health

Grant: 5R35GM138217-02

Peptides and Small-molecules Targeting Signaling Proteins and Protein-Protein Interfaces

FWCI

1.51

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/25/10/5368/pdf?version=1715694238

publisherhttps://www.mdpi.com/1422-0067/25/10/5368/pdf?version=1715694238

publisherhttps://www.mdpi.com/1422-0067/25/10/5368/pdf

journalhttps://doi.org/10.3390/ijms25105368

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38791406

Fields of Study

Bioactive Compounds and Antitumor AgentsEstrogen and related hormone effectsGrowth Hormone and Insulin-like Growth Factors0301 basic medicine0303 health sciences03 medical and health sciencesHumansAllosteric RegulationAllosteric SiteHydrogen BondingIndolesModels, MolecularMolecular Dynamics SimulationProtein BindingProtein Kinase InhibitorsReceptor, IGF Type 1Structure-Activity Relationship

MeSH Terms

Allosteric RegulationAllosteric SiteHumansHydrogen BondingIndolesModels, MolecularProtein BindingStructure-Activity RelationshipReceptor, IGF Type 1Protein Kinase InhibitorsMolecular Dynamics Simulation

Keywords

Allosteric regulationPharmacophoreChemistryIndole testStereochemistryHydrogen bondMolecular dynamicsAffinitiesReceptorMoleculeBiochemistryComputational chemistryMolecular dockingPharmacophore ModelingAllosteric InhibitorsInsulin-like Growth Factor Receptor 1 KinaseModels, MolecularIndolesHydrogen BondingMolecular Dynamics SimulationArticleReceptor, IGF Type 1Structure-Activity RelationshipHumansProtein Kinase InhibitorsAllosteric SiteProtein Binding

Structural Models for a Series of Allosteric Inhibitors of IGF1R Kinase

FAIR Checklist

Authors (2)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)