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PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice

International Journal of Molecular Sciences(2025)10.3390/ijms26073356Source: DataRank Database

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice is a research paper published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0.269. It has been cited 5 times, with 5 citing works in its 1-hop citation network.

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0.269DataRank · unranked

Scored on demand from live citation data

Open Access5 citations · 5 citing works in its network

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Linked data & code

gen refsnp refseq

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (12 grants)OA: goldTopics (49)IDs (PubMed, PMC)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.269

From this paper's citation signal

Citation Network Contribution

From 0 citing papers with measurable signal

This paper's DataRank is currently driven only by its base citation score. None of the citing papers had measurable citation signal.

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Authors (10)

Ali Shawki ORCID,Alina N. Santos ORCID,Vinicius Canale ORCID,Salomon Manz ORCID,Meli’sa S. Crawford ORCID

Live enrichment

PubMed:40244226 PMC:PMC11989999

UCR-City of Hope CUBRI Award

Grant: 2016

NIAID NIH HHS

Grant: R01 AI153314

NIH

Grant: 2R01-DK091281

NIAID NIH HHS

Grant: R21 AI152017

Swiss National Science Foundation Advanced Postdoctoral Mobility Grant

Grant: 177932

Consequences of Epithelial Barrier Defects on Intestinal Macrophage Function

NIH HHS

Grant: 1R01AI153314-01

Tyrosine Phosphatase Regulation of Mucosal Macrophage-Epithelial Cell Cross-talk

NIH

Grant: 1R01DK138456-01

Targeted Identification of IBD Risk Gene Variant Impact on Immune-Epithelial Crosstalk and Intestinal Barrier Function

NIDDK NIH HHS

Grant: R01 DK091281

NIDDK NIH HHS

Grant: R01 DK138456

National Institutes of Health

Grant: 5R01DK091281-07

A novel role for PTPN2 in intestinal epithelial barrier regulation

National Institutes of Health

Grant: 1R21AI152017-01A1

Inflammatory Bowel Disease Susceptibility Gene Regulation of Anemia

Swiss National Science Foundation

Grant: 153314

Metal Oxides as Sulphur Sorbents for use in Supercritical Algae Gasification - An in & ex situ XAS Study

goldLicense: CC BY

Europe_PMChttps://europepmc.org/articles/PMC11989999

Europe_PMChttps://europepmc.org/articles/PMC11989999?pdf=render

https://doi.org/10.3390/ijms26073356

https://pubmed.ncbi.nlm.nih.gov/40244226

http://dx.doi.org/10.3390/ijms26073356

Fields of Study

03 medical and health sciences0302 clinical medicine

MeSH Terms

AnimalsMice, Inbred C57BLMice, KnockoutHumansMiceInflammatory Bowel DiseasesAnemia, Iron-DeficiencyDisease Models, AnimalIronCation Transport ProteinsProteomicsHomeostasisAdultFemaleMaleProtein Tyrosine Phosphatase, Non-Receptor Type 2Iron DeficienciesSolute Carrier Family 11, Member 2

Keywords

Anemiairon deficiencyInflammatory Bowel DiseaseMaleProteomicsAdultKnockoutIronInbred C57BLArticleMiceAnimalsHumansHomeostasisNon-Receptor Type 2Cation Transport ProteinsMice, KnockoutProtein Tyrosine Phosphatase, Non-Receptor Type 2Anemia, Iron-DeficiencyAnimalIron-DeficiencyIron DeficienciesInflammatory Bowel DiseasesMice, Inbred C57BLDisease Models, AnimalSolute Carrier Family 11, Member 2Disease ModelsFemaleProtein Tyrosine Phosphatase

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice

FAIR Checklist

DataRank Breakdown

Authors (10)

Funding (12 grants)

Open Access

Topics

Annotations (Europe PMC)