Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Gasdermin-D Genetic Knockout Reduces Inflammasome-Induced Disruption of the Gut-Brain Axis After Traumatic Brain Injury

International Journal of Molecular Sciences(2025)10.3390/ijms26083512Source: DataRank Database

Gasdermin-D Genetic Knockout Reduces Inflammasome-Induced Disruption of the Gut-Brain Axis After Traumatic Brain Injury is a research paper published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

Download PDF

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 0.42)OA: goldTopics (69)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (8)

Helen M. Bramlett ORCID,Oliver Umland ORCID,Leo I. Levine,Robert W. Keane ORCID,Juan Pablo de Rivero Vaccari ORCID

Live enrichment

PubMed:40331993 PMC:PMC12027180 OpenAlex:https://openalex.org/W4409297274

NINDS/NIA

Grant: 1RF1NS125578-01

The Importance of Abnormal Inflammasome Activation as a Risk Factor between Traumatic Brain Injury and Alzheimer’s Disease

NINDS/NIA

Grant: 1R37NS133195-01

Human Schwann Cell-Derived Exosome Treatment for Traumatic Brain Injury

NINDS/NIA

Grant: R01NS113969

NINDS NIH HHS

Grant: RF1 NS125578

NINDS NIH HHS

Grant: R37 NS133195

NIH HHS

Grant: 1RF1NS125578-01, 1R37NS133195-01, R01NS113969

National Institutes of Health

Grant: 5R01NS113969-03

Role of ASC in TBI-Mediated Systemic Inflammation.

Fundação para a Ciência e a Tecnologia, I.P.

Grant: PTDC/CCI-BIO/29266/2017

Deep Drug Discovery and Deployment

FWCI

0.42

Citation Percentile

0.6%

Citation Trend

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/26/8/3512/pdf?version=1744188116

publisherhttps://www.mdpi.com/1422-0067/26/8/3512/pdf?version=1744188116

publisherhttps://www.mdpi.com/1422-0067/26/8/3512/pdf

journalhttps://doi.org/10.3390/ijms26083512

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40331993

Fields of Study

Inflammasome and immune disordersExtracellular vesicles in diseaseHeme Oxygenase-1 and Carbon Monoxide03 medical and health sciences0302 clinical medicineAnimalsBrain Injuries, TraumaticInflammasomesPhosphate-Binding ProteinsMiceMice, KnockoutMice, Inbred C57BLMaleExtracellular VesiclesIntracellular Signaling Peptides and ProteinsBrainInterleukin-1betaDisease Models, AnimalGastrointestinal TractCytokinesGasdermins

MeSH Terms

Extracellular VesiclesBrain Injuries, TraumaticGasderminsAnimalsBrainDisease Models, AnimalMaleMice, Inbred C57BLCytokinesMice, KnockoutPhosphate-Binding ProteinsGastrointestinal TractIntracellular Signaling Peptides and ProteinsMiceInterleukin-1betaInflammasomes

Keywords

InflammasomeTraumatic brain injuryInflammationKnockout mouseCaspase 1MedicinePathologyImmunologyInternal medicineReceptorIL-1βInterleukinExosomesExtracellular VesiclesPyroptosisGut DysfunctionMaleInflammasomesInterleukin-1betaArticleMiceGasderminsBrain Injuries, TraumaticAnimalsMice, KnockoutIntracellular Signaling Peptides and ProteinsBrainPhosphate-Binding ProteinsMice, Inbred C57BLGastrointestinal TractDisease Models, AnimalCytokines

Sustainable Development Goals

SDG 0: Good health and well-being