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Hypercapnia Increases Influenza A Virus Infection of Bronchial Epithelial Cells by Augmenting Cellular Cholesterol via mTOR and Akt

International Journal of Molecular Sciences(2025)10.3390/ijms26094133Source: DataRank Database

Hypercapnia Increases Influenza A Virus Infection of Bronchial Epithelial Cells by Augmenting Cellular Cholesterol via mTOR and Akt is a research paper published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Scored on demand from live citation data

Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 2.19)OA: goldTopics (62)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Aiko Matsuda,Peter H. S. Sporn ORCID,S. Marina Casalino‐Matsuda ORCID,Fei Chen ORCID

Live enrichment

PubMed:40362373 PMC:PMC12071803 OpenAlex:https://openalex.org/W4409885323

National Institutes of Health

Grant: R01HL131745

National Institutes of Health

Grant: Merit Review I01 CX002350

Merit Review

Grant: I01 CX002350 Department of Veterans Affairs

CSRD VA

Grant: I01 CX002350

National Institutes of Health

Grant: 5P30CA060553-12

The Robert H.Lurie Comprehensive Cancer Center

National Institutes of Health

Grant: 5R01HL131745-03

Hypercapnia and Suppression of Anti-viral Host Defense

FWCI

2.19

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/26/9/4133/pdf?version=1745667938

publisherhttps://www.mdpi.com/1422-0067/26/9/4133/pdf?version=1745667938

publisherhttps://www.mdpi.com/1422-0067/26/9/4133/pdf

journalhttps://doi.org/10.3390/ijms26094133

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40362373

Fields of Study

Influenza Virus Research Studiesinterferon and immune responsesRNA modifications and cancerTOR Serine-Threonine KinasesAnimalsProto-Oncogene Proteins c-aktCholesterolInfluenza A virusHypercapniaMiceEpithelial CellsVirus ReplicationHumansSterol Regulatory Element Binding Protein 2BronchiOrthomyxoviridae InfectionsVirus InternalizationSignal Transduction

MeSH Terms

AnimalsBronchiCholesterolEpithelial CellsHumansHypercapniaOrthomyxoviridae InfectionsInfluenza A virusVirus ReplicationSignal TransductionProto-Oncogene Proteins c-aktMiceSterol Regulatory Element Binding Protein 2Virus InternalizationTOR Serine-Threonine Kinases

Keywords

PI3K/AKT/mTOR pathwayInternalizationProtein kinase BViral replicationHypercapniaBiologyInfluenza A virusCell biologyImmunologyVirusSignal transductionEndocrinologyCellBiochemistryCholesterolMtorAKTTOR Serine-Threonine KinasesEpithelial CellsBronchiVirus InternalizationVirus ReplicationArticleMiceOrthomyxoviridae InfectionsAnimalsHumansProto-Oncogene Proteins c-aktSterol Regulatory Element Binding Protein 2

Sustainable Development Goals

SDG 0: Good health and well-being