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APOE Genotype-Stratified Meta-Analysis of Cognitive Decline Reveals Novel Loci for Language and Global Cognitive Function in Older Adults

International Journal of Molecular Sciences(2025)10.3390/ijms26146940Source: DataRank Database

APOE Genotype-Stratified Meta-Analysis of Cognitive Decline Reveals Novel Loci for Language and Global Cognitive Function in Older Adults is a research paper published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (17 grants)Impact (FWCI 0.45)OA: goldTopics (75)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Kang-Hsien Fan ORCID,Beth E. Snitz ORCID,Mary Ganguli ORCID,Steven T. DeKosky ORCID,Oscar L. Lopez

Live enrichment

PubMed:40725187 PMC:PMC12295717 OpenAlex:https://openalex.org/W4412516372

National Institutes of Health (NIH)

Grant: AG030653

National Institutes of Health (NIH)

Grant: AG041718

National Institutes of Health (NIH)

Grant: AG064877

National Institutes of Health (NIH)

Grant: R37 AG023651

National Institutes of Health (NIH)

Grant: AG07562

National Institutes of Health (NIH)

Grant: P30 AG066468

National Institutes of Health (NIH)

Grant: U24 AG021886

National Institutes of Health (NIH)

Grant: U01 AT000162

National Institutes of Health (NIH)

Grant: AG030653, AG041718, AG064877, AG023651, AG07562 and P30 AG066468

National Institutes of Health

Grant: 3R01AG030653-06A1S1

Search for the Alzheimers Genes

National Institutes of Health

Grant: 5U24AG021886-18

National Cell Repository for Alzheimer's Disease (NCRAD)

National Institutes of Health

Grant: 5R01AG007562-11

EPIDEMIOLOGY OF DEMENTIA: A PROSPECTIVE COMMUNITY STUDY

National Institutes of Health

Grant: 5R37AG023651-17

Mild Cognitive Impairment: A Prospective Community Study

National Institutes of Health

Grant: 3R01AG064877-02S1

Genetic Architecture of Alzheimer’s disease Proteinopathies

National Institutes of Health

Grant: 3P30AG066468-01S1

Comparison of tau-PET tracers: Progress towards a universal measure

National Institutes of Health

Grant: 5U01AT000162-10

Ginkgo Biloba Prevention Trial in Older Individuals

National Institutes of Health

Grant: 5R01AG041718-03

Deep Resequencing of Candidate Gene Regions in Late-onset Alzheimer's Disease

FWCI

0.45

Citation Percentile

0.6%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/26/14/6940/pdf?version=1752915083

publisherhttps://www.mdpi.com/1422-0067/26/14/6940/pdf?version=1752915083

publisherhttps://www.mdpi.com/1422-0067/26/14/6940/pdf

journalhttps://doi.org/10.3390/ijms26146940

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40725187

Fields of Study

Genetic Associations and EpidemiologyDiet and metabolism studiesBioinformatics and Genomic NetworksHumansAgedCognitive DysfunctionGenotypeGenome-Wide Association StudyCognitionMaleLanguageFemaleApolipoproteins EGenetic LociApolipoprotein E4Polymorphism, Single NucleotideAllelesAged, 80 and overGenetic Predisposition to Disease

MeSH Terms

AgedAged, 80 and overAllelesApolipoproteins ECognitionFemaleGenotypeHumansLanguageMaleGenetic Predisposition to DiseasePolymorphism, Single NucleotideApolipoprotein E4Genome-Wide Association StudyGenetic LociCognitive Dysfunction

Keywords

CognitionApolipoprotein EGenotypeMeta-analysisCognitive declineGerontologyCognitive agingPsychologyGeneticsBiologyMedicineDementiaDiseaseNeuroscienceGeneInternal medicineMemoryAttentionLanguageGenome-wide AssociationExecutive FunctionVisuospatial FunctionGlobal Cognitive FunctionNeurocognitive DomainsApoe-StratifiedMale<i>APOE</i>-stratifiedApolipoprotein E4Polymorphism, Single NucleotideArticleApolipoproteins EHumansCognitive DysfunctionGenetic Predisposition to DiseaseAllelesAgedAged, 80 and overGenetic LociFemaleGenome-Wide Association Study