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CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway

International Journal of Molecular Sciences(2025)10.3390/ijms26188991Source: DataRank Database

CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway is a research paper published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 0.00)OA: goldTopics (55)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Carmina S. Patrick ORCID,Stefan Hinz ORCID,Mark A. LaBarge ORCID,Leslie A. Lange ORCID,Susan L. Neuhausen ORCID

Live enrichment

PubMed:41009559 PMC:PMC12470006 OpenAlex:https://openalex.org/W4414249271

NIH HHS/United States and the Burroughs Wellcome Fund Postdoctoral Enrichment Program

Grant: 1277523

NIH HHS/United States and the Burroughs Wellcome Fund Postdoctoral Enrichment Program

Grant: PF-21-184-01-CSM

NCI NIH HHS

Grant: T32 CA221709

NIH HHS

Grant: 2T32CA221709-06A1

National Institutes of Health

Grant: 5T32CA221709-02

Cancer Metabolism Training Program

FWCI

0.00

Citation Percentile

0.1%

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/26/18/8991/pdf?version=1758009359

publisherhttps://www.mdpi.com/1422-0067/26/18/8991/pdf?version=1758009359

publisherhttps://www.mdpi.com/1422-0067/26/18/8991/pdf

journalhttps://doi.org/10.3390/ijms26188991

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41009559

Fields of Study

Connective Tissue Growth Factor Research0301 basic medicine03 medical and health sciencesCysteine-Rich Protein 61HumansMaleInsulin-Like Growth Factor IProstatic NeoplasmsCell ProliferationProto-Oncogene Proteins c-aktPhosphatidylinositol 3-KinasesSignal TransductionCell Line, TumorGene Expression Regulation, NeoplasticCell Movement

MeSH Terms

Cell MovementHumansInsulin-Like Growth Factor IMaleProstatic NeoplasmsSignal TransductionGene Expression Regulation, NeoplasticPhosphatidylinositol 3-KinasesCell Line, TumorCell ProliferationProto-Oncogene Proteins c-aktCysteine-Rich Protein 61

Keywords

CYR61Prostate cancerGene silencingGene knockdownDU145Cell growthSignal transductionSmall interfering RNAAutocrine signallingMetabolismMAPKMetastasisIgf1Pi3/aktMaleBiology and Life SciencesProstatic NeoplasmsArticleGene Expression Regulation, NeoplasticPhosphatidylinositol 3-KinasesCell MovementCell Line, TumorHumansOtherInsulin-Like Growth Factor IProto-Oncogene Proteins c-aktCysteine-Rich Protein 61Cell Proliferation