Multimodal Integration of Genomic Data Reveals Regulatory Mechanisms at the Polycystic Ovary Syndrome (PCOS)-Associated 12q13.2 Locus is a dataset published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0, placing it in the top 100% of the data-sharing corpus. Its calibrated FAIR score is 52/100.
Ranks in the top 100% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“The 10× Cell Ranger filtered feature-barcode matrix data files and the scRNA-seq data are publicly available for download at https://zenodo.org/record/7942968 (accessed on 1 October 2025).”
A web address (https://zenodo.org/record/7942968) is given; no DOI or repository accession in a PID scheme is provided.
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“The 10× Cell Ranger filtered feature-barcode matrix data files and the scRNA-seq data are publicly available for download at https://zenodo.org/record/7942968 (accessed on 1 October 2025).”
Zenodo is a named data repository (listed in re3data/FAIRsharing).
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“The 10× Cell Ranger filtered feature-barcode matrix data files and the scRNA-seq data are publicly available for download at https://zenodo.org/record/7942968 (accessed on 1 October 2025).”
The dataset identifier (Zenodo URL) appears only in the body text, not in the reference list.
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“The 10× Cell Ranger filtered feature-barcode matrix data files and the scRNA-seq data are publicly available for download at https://zenodo.org/record/7942968 (accessed on 1 October 2025).”
The statement points to a repository record (Zenodo record) with a link, matching Colavizza category 3.
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“The 10× Cell Ranger filtered feature-barcode matrix data files and the scRNA-seq data are publicly available for download at https://zenodo.org/record/7942968 (accessed on 1 October 2025).”
The dataset's content is described in running prose only ('filtered feature-barcode matrix data files and the scRNA-seq data') without an itemised inventory.
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“The 10× Cell Ranger filtered feature-barcode matrix data files and the scRNA-seq data are publicly available for download at https://zenodo.org/record/7942968 (accessed on 1 October 2025).”
The route to the data carries no stated precondition; it is described as 'publicly available for download'.
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“The 10× Cell Ranger filtered feature-barcode matrix data files and the scRNA-seq data are publicly available for download at https://zenodo.org/record/7942968 (accessed on 1 October 2025).”
The paper explicitly labels the data as 'publicly available', which is a natural-language synonym for open access.
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The data are human-subject but publicly available; no gatekeeper of any kind is named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
“publicly available for download”
The paper states the data are available now but does not specify how long they will persist. [majority verdict 'partial' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
No file-format token (e.g., CSV, HDF5, FASTQ) is named for the released data.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
No data or metadata community standard (e.g., MIAME, MINSEQE) is named; the paper uses only software tools and generic protocols.
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“The ERBB3 missense variant (rs773123 https://www.ncbi.nlm.nih.gov/snp/rs773123 , accessed on 14 November 2025) had a CADD PHRED score of 24.1.”
The paper gives dbSNP rs IDs (e.g., rs773123) which are identifiers for external variant resources used in the analysis. [majority verdict 'yes' (4/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No reuse license or terms document is named for the data; the article is CC BY but that license is for the paper, not the data.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
“The 10× Cell Ranger filtered feature-barcode matrix data files and the scRNA-seq data are publicly available for download at https://zenodo.org/record/7942968 (accessed on 1 October 2025).”
No version token is given; the access date (1 October 2025) pins the snapshot.
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
No code locator (repository URL, DOI, or package identifier) is provided; the only offer is not stated.
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“This research was funded by the National Institutes of Health, grant numbers R01HD083323 (J.M.M. and J.F.S.III) and R01HD033852 (J.M.M.), and a Penn State College of Medicine Bridge Grant (J.M.M).”
Award numbers (R01HD083323, R01HD033852) are attached to named funders. [majority verdict 'yes' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“Libraries were sequenced on an Illumina NextSeq 500 to generate 91 bp reads.”
The paper names specific instruments and software (Illumina NextSeq 500, Cell Ranger v6.1.1, Seurat v4.1.1, etc.) used to produce the data.
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No README, data dictionary, or codebook is mentioned as accompanying the deposited data; variable definitions are only inside the article (Table 1).
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
National Institutes of Health
Grant: R01HD083323
National Institutes of Health
Grant: R01HD033852
NIH HHS
Grant: 5R01HD083323-05
NIEHS NIH HHS
Grant: P30 ES013508
NIH HHS
Grant: 5R01HD033852-13
MeSH Terms
Keywords