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β2E153 Residue at Loop B of GABAAR Is Involved in Agonist Stabilization and Gating Properties

International Journal of Molecular Sciences(2025)10.3390/ijms27010047Source: DataRank Database

β2E153 Residue at Loop B of GABAAR Is Involved in Agonist Stabilization and Gating Properties is a research paper published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)Impact (FWCI 0.00)OA: goldTopics (41)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Aleksandra Brzóstowicz,Jerzy W. Mozrzymas ORCID,Michał A. Michałowski ORCID

Live enrichment

PubMed:41515928 OpenAlex:https://openalex.org/W7116727222

National Science Centre

Grant: 2015/18/A/NZ1/00395

National Science Centre

Grant: 2021/43/B/NZ4/01675

FWCI

0.00

Citation Percentile

0.5%

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/27/1/47/pdf

publisherhttps://www.mdpi.com/1422-0067/27/1/47/pdf

journalhttps://doi.org/10.3390/ijms27010047

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41515928

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12785432/

Fields of Study

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology ResearchIon channel regulation and functionReceptors, GABA-AIon Channel GatingAnimalsKineticsHumansModels, Moleculargamma-Aminobutyric AcidPatch-Clamp TechniquesGABA-A Receptor AgonistsMutation

MeSH Terms

AnimalsBinding Sitesgamma-Aminobutyric AcidHumansKineticsModels, MolecularMutationReceptors, GABA-AIon Channel GatingPatch-Clamp TechniquesHEK293 CellsGABA-A Receptor Agonists

Keywords

GatingAllosteric regulationAgonistExtracellularIon channelBinding siteReceptorLoop (graph theory)GABAgatedkineticsligandmodelmutationpatch clampstructure