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Curcuminoids Activate TET Enzymes and Increase DNA Hydroxymethylation and Active Demethylation in Leukemia Cells

International Journal of Molecular Sciences(2025)10.3390/ijms27010310Source: DataRank Database

Curcuminoids Activate TET Enzymes and Increase DNA Hydroxymethylation and Active Demethylation in Leukemia Cells is a research paper published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (1 grants)Impact (FWCI 0.00)OA: goldTopics (47)IDs (PubMed, PMC, OpenAlex)SDGs (1)

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Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Suhila Sawesi ORCID,Botao Peng,Badreldeen Rashrash,Hailey Cox,Tamer E. Fandy ORCID

Live enrichment

PubMed:41516186 PMC:PMC12785487 OpenAlex:https://openalex.org/W7117454063

National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health

Grant: P20GM103434

FWCI

0.00

Citation Percentile

0.4%

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/27/1/310/pdf?version=1766831668

publisherhttps://www.mdpi.com/1422-0067/27/1/310/pdf?version=1766831668

publisherhttps://www.mdpi.com/1422-0067/27/1/310/pdf

journalhttps://doi.org/10.3390/ijms27010310

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41516186

Fields of Study

Curcumin's Biomedical ApplicationsEpigenetics and DNA MethylationRetinoids in leukemia and cellular processesHumansDNA MethylationLeukemiaCurcumin5-MethylcytosineCpG IslandsPromoter Regions, GeneticProto-Oncogene ProteinsDNA-Binding ProteinsCell Line, TumorDNA DemethylationEpigenesis, GeneticDioxygenasesMixed Function Oxygenases

MeSH Terms

DNA DemethylationCurcuminDNA-Binding ProteinsHumansMixed Function OxygenasesLeukemiaPromoter Regions, GeneticProto-Oncogene ProteinsCpG IslandsDNA MethylationEpigenesis, Genetic5-MethylcytosineCell Line, TumorDioxygenases

Keywords

DNA demethylationDNA methylationDemethylationCpG siteEpigeneticsBisulfite sequencingMethylationGene expressionPromoterLeukemiaCurcuminDimethoxycurcuminDna HydroxymethylationTet EnzymesActive DemethylationOxidative Bisulfite Sequencing (Oxbs)

Sustainable Development Goals

SDG 0: Life below water