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Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA

Molecules(2020)10.3390/molecules25071760Source: DataRank Database

Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA is a research paper published in Molecules (2020). On theSindex it has a DataRank of 0. It has been cited 17 times.

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Enrichment:Funding (10 grants)OA: goldTopics (44)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Lois Tolvinski ORCID,Edward R. Zartler ORCID,Anna Moberg,Åsa Frostell,Garry R. Smith ORCID

Live enrichment

PubMed:32290261 PMC:PMC7180839

Wellcome Trust

Grant: WT096496/Z/11/Z

National Institutes of Health

Grant: 5R01CA186775

NCI NIH HHS

Grant: R01 CA117830

NCI NIH HHS

Grant: P30 CA010815

NCI NIH HHS

Grant: R01 CA093606

National Institutes of Health

Grant: 2R01CA117830-06

Regulation of KSHV Latency

National Institutes of Health

Grant: 5R01DE017336-12

Epigenetic Regulation of Epstein-Barr Virus

National Institutes of Health

Grant: 5R01CA186775-03

Development of a Small Molecule Inhibitor for KSHV LANA

National Institutes of Health

Grant: 5R01CA093606-13

Regulation of EBV Latency by EBNA1

Wellcome Trust

Grant: 096496

Development of a small molecule inhibitor of EBNA1 to treat Epstein-Barr Virus(EBV) Latent Infection and Associated Disease.

goldLicense: cc-by

publisherhttps://www.mdpi.com/1420-3049/25/7/1760/pdf?version=1586764757

publisherhttps://www.mdpi.com/1420-3049/25/7/1760/pdf

repositoryhttps://doaj.org/article/551662039b294cbb86386a77fdca0133

repositoryhttp://dx.doi.org/10.3390/molecules25071760

repositoryhttps://www.osti.gov/biblio/1630327

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansHerpesvirus 4, HumanHerpesvirus 8, HumanDNA-Binding ProteinsNuclear ProteinsDNA, ViralEpstein-Barr Virus Nuclear AntigensAntigens, ViralLigandsMagnetic Resonance SpectroscopyStructure-Activity RelationshipModels, MolecularGammapapillomavirusSmall Molecule LibrariesDrug Discovery

Keywords

Surface plasmon resonanceLatency-associated Nuclear AntigenEpstein–barr VirusProtein–dna InteractionFragment-based Lead DiscoveryKaposi’s Sarcoma Associated Herpesvirus (Kshv)Epstein–barr Nuclear Antigen 1Saturation Transfer Difference-nuclear Magnetic ResonanceModels, MolecularHerpesvirus 4, HumanMagnetic Resonance SpectroscopyGammapapillomavirusOrganic chemistryLigandsArticleSmall Molecule LibrariesStructure-Activity RelationshipQD241-441Drug DiscoveryHumansAntigens, ViralNuclear ProteinsDNA-Binding ProteinsEpstein-Barr Virus Nuclear AntigensDNA, ViralHerpesvirus 8, Human

Sustainable Development Goals

SDG 3: 3. Good health

Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA

FAIR Checklist

Authors (8)

Funding (10 grants)

Open Access

Topics

Annotations (Europe PMC)