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Design, Synthesis, and Antitumor Activity of a Series of Novel 4-(Aromatic Sulfonyl)-1-oxa-4-azaspiro[4.5]deca-6,9-dien-8-ones

Molecules(2020)10.3390/molecules25225459Source: DataRank Database

Design, Synthesis, and Antitumor Activity of a Series of Novel 4-(Aromatic Sulfonyl)-1-oxa-4-azaspiro[4.5]deca-6,9-dien-8-ones is a research paper published in Molecules (2020). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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Enrichment:Funding (4 grants)Impact (FWCI 0.19)OA: goldTopics (65)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Chen Chen ORCID,Qiu Zhong,Shilong Zheng ORCID,Guangdi Wang ORCID,Ling He ORCID

Live enrichment

PubMed:33233396 PMC:PMC7700525 OpenAlex:https://openalex.org/W3110571789

National Institute on Minority Health and Health Disparities

Grant: U54MD007595

Sichuan University-Lu Zhou Strategic Cooperation Projects

Grant: 2017 CDLZ-S34

NIMHD NIH HHS

Grant: G12 MD007595

National Institutes of Health

Grant: 2G12MD007595-06

Collaborations and Partnerships

FWCI

0.19

Citation Percentile

0.4%

Citation Trend

2022

2024

goldLicense: cc-by

journalhttps://www.mdpi.com/1420-3049/25/22/5459/pdf?version=1606186953

publisherhttps://www.mdpi.com/1420-3049/25/22/5459/pdf?version=1606186953

publisherhttps://www.mdpi.com/1420-3049/25/22/5459/pdf

journalhttps://doi.org/10.3390/molecules25225459

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33233396

Fields of Study

Synthesis and Biological EvaluationSynthesis and Catalytic ReactionsSulfur-Based Synthesis Techniques0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsAntineoplastic AgentsApoptosisCell Cycle CheckpointsCell Line, TumorCell ProliferationDrug DesignFemaleHumansMaleMiceSpiro CompoundsToxicity Tests, Acute

MeSH Terms

AnimalsAntineoplastic AgentsFemaleHumansMaleSpiro CompoundsDrug DesignApoptosisToxicity Tests, AcuteCell Line, TumorCell ProliferationMiceCell Cycle Checkpoints

Keywords

SulfonylChemistryHeLaApoptosisDeca-StereochemistryFlow cytometryMannoseDerivative (finance)Combinatorial chemistryCellMedicinal chemistryBiochemistryOrganic chemistryMolecular biologyBiologyAntitumor activityMetal-catalyzed Cascade CyclizationSulfonylazaspirodienoneMaleAntineoplastic AgentsCell Cycle CheckpointsArticleMiceQD241-441Cell Line, TumorDrug DesignToxicity Tests, AcuteAnimalsHumansFemaleSpiro CompoundsCell Proliferation

Sustainable Development Goals

SDG 3: 3. Good healthSDG 7: 7. Clean energySDG 0: Good health and well-being

Design, Synthesis, and Antitumor Activity of a Series of Novel 4-(Aromatic Sulfonyl)-1-oxa-4-azaspiro[4.5]deca-6,9-dien-8-ones

FAIR Checklist

Authors (6)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)