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Ligand-Free Signaling of G-Protein-Coupled Receptors: Relevance to μ Opioid Receptors in Analgesia and Addiction

Molecules(2022)10.3390/molecules27185826Source: DataRank Database

Ligand-Free Signaling of G-Protein-Coupled Receptors: Relevance to μ Opioid Receptors in Analgesia and Addiction is a research paper published in Molecules (2022). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Scored on demand from live citation data

Open Access7 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.47)OA: goldTopics (30)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

John C. McKew ORCID,Wolfgang Sadée ORCID

Live enrichment

PubMed:36144565 OpenAlex:https://openalex.org/W4296137051

NICHD

Grant: R21HD085496

NICHD

Grant: R44DA045414

NICHD

Grant: 2020-04

FWCI

0.47

Citation Percentile

0.6%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1420-3049/27/18/5826/pdf?version=1662639219

publisherhttps://www.mdpi.com/1420-3049/27/18/5826/pdf?version=1662639219

publisherhttps://www.mdpi.com/1420-3049/27/18/5826/pdf

journalhttps://doi.org/10.3390/molecules27185826

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36144565

Fields of Study

Receptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyPhosphodiesterase function and regulation

MeSH Terms

AnalgesiaAnalgesics, OpioidHumansLigandsMorphineNaloxoneNaltrexoneNarcotic AntagonistsOpioid-Related DisordersPainReceptors, Opioid, mu

Keywords

NaltrexoneOpioidPharmacologyChemistryAgonistG protein-coupled receptorReceptorLigand (biochemistry)(+)-Naloxoneμ-opioid receptorOpioid receptorFunctional selectivityIntrinsic activityInverse agonistMedicineBiochemistry

Sustainable Development Goals

SDG 0: Good health and well-being