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Design, Synthesis, and Anti-Leukemic Evaluation of a Series of Dianilinopyrimidines by Regulating the Ras/Raf/MEK/ERK and STAT3/c-Myc Pathways

Molecules(2024)10.3390/molecules29071597Source: DataRank Database

Design, Synthesis, and Anti-Leukemic Evaluation of a Series of Dianilinopyrimidines by Regulating the Ras/Raf/MEK/ERK and STAT3/c-Myc Pathways is a research paper published in Molecules (2024). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 0.38)OA: goldTopics (31)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Bo Wang ORCID,Yu Mou ORCID,Xiang Liu ORCID,Qiqing Chen ORCID,Weidong Pu

Live enrichment

PubMed:38611876 PMC:PMC11013136 OpenAlex:https://openalex.org/W4393866892

National Natural Science Foundation of China

Grant: 82360035

National Natural Science Foundation of China

Grant: 81960546

National Natural Science Foundation of China

Grant: 81872772

National Natural Science Foundation of China

Grant: 82260040

National Natural Science Foundation of China

Grant: 82160808

National Natural Science Foundation of China

Grant: 82060738

National Natural Science Foundation of China

Grant: QKHPTRC [2020]5008

National Natural Science Foundation of China

Grant: QKHZC [2020]4Y203

National Natural Science Foundation of China

Grant: QKHJC-ZK [2021]YB569

National Natural Science Foundation of China

Grant: QKHJC-ZK[2022]YB293

National Natural Science Foundation of China

Grant: QKHJC-ZK[2023]YB240

National Natural Science Foundation of China

Grant: RN21025

National Natural Science Foundation of China

Grant: RN21024

National Natural Science Foundation of China

Grant: FAMP202005K

National Natural Science Foundation of China

Grant: QKHRCPT [2019]5106

the Guizhou Provincial Natural Science Foundation

Grant: QKHPTRC [2020]5008, QKHZC [2020]4Y203, QKHJC-ZK[2021]YB569, QKHJC-ZK[2022]YB293, QKHJC-ZK[2023]YB240

National Natural Science Foundation of China

Grant: 82360035, 81960546, 81872772, 82260040, 82160808 and 82060738

the Guizhou Medical University Research Grant

Grant: RN21025 and RN21024

FWCI

0.38

Citation Percentile

0.5%

Citation Trend

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/1420-3049/29/7/1597/pdf?version=1712114670

publisherhttps://www.mdpi.com/1420-3049/29/7/1597/pdf?version=1712114670

publisherhttps://www.mdpi.com/1420-3049/29/7/1597/pdf

journalhttps://doi.org/10.3390/molecules29071597

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38611876

Fields of Study

Synthesis and biological activityQuinazolinone synthesis and applicationsCancer therapeutics and mechanisms

MeSH Terms

AnimalsLeukemia, Erythroblastic, AcuteHumansLeukemiaPhosphorylationProtein Serine-Threonine KinasesDimerizationMitogen-Activated Protein Kinase KinasesSTAT3 Transcription FactorMice

Keywords

MAPK/ERK pathwayKinaseCell cycleSTAT3ApoptosisCancer researchBiologyPhosphorylationCyclin-dependent kinase 1Molecular biologyProtein kinase ACell biologyChemistryBiochemistryLeukemiaRas/raf/mer/erkStat3/c-mycDianilinopyrimidines

Sustainable Development Goals

SDG 0: Good health and well-being

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