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Rational Design, Synthesis, Molecular Docking, and Biological Evaluations of New Phenylpiperazine Derivatives of 1,2-Benzothiazine as Potential Anticancer Agents

Molecules(2024)10.3390/molecules29184282Source: DataRank Database

Rational Design, Synthesis, Molecular Docking, and Biological Evaluations of New Phenylpiperazine Derivatives of 1,2-Benzothiazine as Potential Anticancer Agents is a research paper published in Molecules (2024). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (2 grants)OA: goldTopics (21)IDs (PubMed, PMC)Annotations (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Natalia Zaręba ORCID,Żaneta Czyżnikowska ORCID,Tomasz Janek ORCID,Marta Kepinská ORCID,Berenika M. Szczęśniak-Sięga ORCID

Live enrichment

PubMed:39339277 PMC:PMC11433925

Ministry of Health

Grant: SUBZ.D020.24.071

Wroclaw Medical University

Grant: SUBZ.D070.24.087

goldLicense: cc-by

publisherhttps://www.mdpi.com/1420-3049/29/18/4282/pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11433925/pdf/molecules-29-04282.pdf

Unpaywallhttps://doi.org/10.3390/molecules29184282

Europe_PMChttps://europepmc.org/articles/PMC11433925

Europe_PMChttps://europepmc.org/articles/PMC11433925?pdf=render

MeSH Terms

Cell Line, TumorHumansPiperazinesThiazinesDoxorubicinDNA Topoisomerases, Type IIAntineoplastic AgentsDrug Screening Assays, AntitumorCell ProliferationMolecular StructureStructure-Activity RelationshipDrug DesignTopoisomerase II InhibitorsMCF-7 CellsMolecular Docking Simulation

Keywords

SynthesisMolecular dockingAnticancerFluorescence spectroscopyTopoisomerase Ii1,2-Benzothiazine