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Effects of Biased Analogues of the Kappa Opioid Receptor Agonist, U50,488, in Preclinical Models of Pain and Side Effects

Molecules(2025)10.3390/molecules30030604Source: DataRank Database

Effects of Biased Analogues of the Kappa Opioid Receptor Agonist, U50,488, in Preclinical Models of Pain and Side Effects is a research paper published in Molecules (2025). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)OA: goldTopics (44)IDs (PubMed)

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Reusable (0/3)

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Authors (9)

Loan Y. Vu ORCID,Lindsay Kornberger,Dan Luo ORCID,Brittany Scouller,Sheein Hong

Live enrichment

PubMed:39942708

Health Research Council of New Zealand

Grant: #22/331

Health Research Council of New Zealand

Grant: U01 DA051377

Health Research Council of New Zealand

Grant: S10 OD28690

Health Research Council of New Zealand

Grant: P20 GM130456

National Institutes of Health

Grant: 1S10OD028690-01

Bruker AVANCE NEO 600 MHz High-Performance Digital NMR Spectrometer

National Institutes of Health

Grant: 5U01DA051377-03

Development of Agents for Synthetic Opioid Overdose

National Institutes of Health

Grant: 5P20GM130456-03

Center of Biomedical Research Excellence in Pharmaceutical Research and Innovation

NIH HHS

Grant: S10 OD028690

Health Research Council of New Zealand

Grant: 22/331

goldLicense: cc-by

publisherhttps://www.mdpi.com/1420-3049/30/3/604/pdf?version=1738162182

publisherhttps://www.mdpi.com/1420-3049/30/3/604/pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11820436/pdf/molecules-30-00604.pdf

repositoryhttps://uknowledge.uky.edu/ps_facpub/219

repositoryhttps://doaj.org/article/17f2c31cf3714c52a18c44781bc0f6da

Fields of Study

AnimalsReceptors, Opioid, kappaMice3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-IsomerDisease Models, AnimalNeuralgiaMaleMice, KnockoutPaclitaxelHumansAnalgesics

MeSH Terms

AnimalsReceptors, Opioid, kappaMice3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-IsomerDisease Models, AnimalNeuralgiaMaleMice, KnockoutPaclitaxelHumansAnalgesics

Keywords

MaleMice, KnockoutAnalgesicsU50,488PaclitaxelReceptors, Opioid, kappa3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-IsomerOrganic chemistryArticleside effectsMiceDisease Models, AnimalQD241-441biased agonismanti-nociceptionsignaling biasAnimalsNeuralgiaHumanspainfunctional selectivitykappa opioid receptor