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Anticancer Quinolinol Small Molecules Target Multiple Pathways to Promote Cell Death and Eliminate Melanoma Cells Resistant to BRAF Inhibitors

Molecules(2025)10.3390/molecules30132696Source: DataRank Database

Anticancer Quinolinol Small Molecules Target Multiple Pathways to Promote Cell Death and Eliminate Melanoma Cells Resistant to BRAF Inhibitors is a research paper published in Molecules (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 0.51)OA: goldTopics (44)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Rati Lama,Alexis D. Kelleher ORCID,Erika Rizzo ORCID,Samuel L. Galster,Chao Xue ORCID

Live enrichment

PubMed:40649216 PMC:PMC12251381 OpenAlex:https://openalex.org/W4411554120

Roswell Park Alliance Foundation

Grant: P30CA016056

Roswell Park Alliance Foundation

Grant: R35 GM153290

Roswell Park Alliance Foundation

Grant: R01 GM078383

Roswell Park Alliance Foundation

Grant: DT Seeds fund to XW and SRC

NIH HHS

Grant: R35 GM153290 (SRC)

FWCI

0.51

Citation Percentile

0.7%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1420-3049/30/13/2696/pdf?version=1750594632

publisherhttps://www.mdpi.com/1420-3049/30/13/2696/pdf?version=1750594632

publisherhttps://www.mdpi.com/1420-3049/30/13/2696/pdf

journalhttps://doi.org/10.3390/molecules30132696

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40649216

Fields of Study

Cancer-related Molecular PathwaysUbiquitin and proteasome pathwaysProtein Degradation and InhibitorsMedicineChemistry

MeSH Terms

Antineoplastic AgentsHumansMelanomaStructure-Activity RelationshipQuinolonesSignal TransductionCell DeathApoptosisDrug Resistance, NeoplasmCell Line, TumorProtein Kinase InhibitorsProto-Oncogene Proteins B-rafCell ProliferationProto-Oncogene Proteins c-mdm2Small Molecule Libraries

Keywords

MelanomaMdm2Clonogenic assayApoptosisUbiquitin ligaseChemistryProgrammed cell deathCancer researchSmall moleculeCancer cellCell biologyBiologyBiochemistryUbiquitinCancerGeneGeneticsCell deathTargetsE3 LigaseMdm2-mdm4QuinolinolMmri62Chemical Robe

Sustainable Development Goals

SDG 0: Good health and well-being