🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Glucagon and Glucose Availability Influence Metabolic Heterogeneity and Malignancy in Pancreatic Neuroendocrine Tumour (pNET) Cells: Novel Routes for Therapeutic Targeting

Molecules(2025)10.3390/molecules30132736Source: DataRank Database

Glucagon and Glucose Availability Influence Metabolic Heterogeneity and Malignancy in Pancreatic Neuroendocrine Tumour (pNET) Cells: Novel Routes for Therapeutic Targeting is a research paper published in Molecules (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 0.77)OA: goldTopics (50)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (11)

Isabel Lemos ORCID,Cindy Mendes ORCID,Beatriz Chumbinho ORCID,Fernanda Silva ORCID,Daniela Pereira ORCID

Live enrichment

PubMed:40649254 PMC:PMC12251001 OpenAlex:https://openalex.org/W4411651498

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: UIDB/04462/2020

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: UIDP/04462/2020

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: UIDB/04612/2020

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: UIDP/04612/2020

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: LA/P/0087/2020

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: TF-2022-24-DC

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: 2020.06956.BD

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: UI/BD/154203/2022

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: SFRH/BPD/111100/2015

Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior (FCT/MCTES, Portugal)

Grant: AAC 01/SAICT/2016

Liga Portuguesa Contra o Cancro

Grant: Terry Fox

Fundação para a Ciência e a Tecnologia

Grant: UIDB/04612/2020 and UIDP/04612/2020

Fundação para a Ciência e a Tecnologia

Grant: UIDB/04462/2020 and UIDP/04462/2020

National Institutes of Health

Grant: 5U2CDK119886-03

National Metabolomics Data Repository - nextgen Metabolomics Workbench

National Institutes of Health

Grant: 3OT2OD030544-01S1

Biomedical Data Commons Workbench (BDCW)

FWCI

0.77

Citation Percentile

0.7%

Citation Trend

2025

goldLicense: cc-by

journalhttps://doi.org/10.3390/molecules30132736

publisherhttps://doi.org/10.3390/molecules30132736

publisherhttps://www.mdpi.com/1420-3049/30/13/2736/pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40649254

repositoryhttp://hdl.handle.net/10362/185539

Fields of Study

Neuroendocrine Tumor Research AdvancesMetabolism, Diabetes, and CancerPancreatic function and diabetes

MeSH Terms

GlucagonGlucoseHumansPancreatic NeoplasmsGene Expression Regulation, NeoplasticNeuroendocrine TumorsCell Line, Tumor

Keywords

GlucagonGlucagon receptorHyperglucagonemiaEndocrinologyInternal medicineBiologyCarbohydrate metabolismGluconeogenesisPancreatic cancerCell cultureDownregulation and upregulationMetabolismGlycolysisCancer researchInsulinBiochemistryCancerMedicineGeneBiomarkersCancer MetabolismGlucagon-like Peptide-1 Receptor (Glp-1r)Glucagon Receptor (Gcgr)Pancreatic Neuroendocrine Tumours (Pnets)Organic ChemistryPharmaceutical ScienceArticleAnalytical ChemistryPancreatic NeoplasmsGene Expression Regulation, NeoplasticNeuroendocrine TumorsQD241-441GlucoseSDG 3 - Good Health and Well-beingChemistry (miscellaneous)Cell Line, TumorDrug DiscoveryMolecular MedicineHumansPhysical and Theoretical Chemistry

Sustainable Development Goals

SDG 0: Good health and well-being

Related Papers (9)

Reduction in Glucagon Receptor Expression by an Antisense Oligonucleotide Ameliorates Diabetic Syndrome indb/dbMice

Diabetes(2004)

OpenAlex related

10.2337/diabetes.53.2.410

The past, present, and future physiology and pharmacology of glucagon

Cell Metabolism(2022)

OpenAlex related

10.1016/j.cmet.2022.10.001

Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia

Diabetes(2020)

OpenAlex related

10.2337/db20-0440

Glucagon receptor signaling in metabolic diseases

Peptides(2018)

OpenAlex related

10.1016/j.peptides.2017.11.016

1952-P: Glucagon Receptor Antagonism Increases Plasma Amino Acids and Glucagon

Diabetes(2019)

OpenAlex related

10.2337/db19-1952-p

Diagnosis and treatment of sulfonylurea-induced hyperinsulinemic hypoglycemia

The American Journal of Emergency Medicine(1997)

OpenAlex related

10.1016/s0735-6757(97)90062-0

Persistent hypoglycemia and hyperinsulinemia: Caution in using glucagon

The American Journal of Emergency Medicine(1996)

OpenAlex related

10.1016/s0735-6757(96)90029-7

Effect of acute glucagon removal on metabolic response to infection in conscious dog

American Journal of Physiology-Endocrinology and Metabolism(1995)

OpenAlex related

10.1152/ajpendo.1995.268.1.e92

1812-P: Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia

Diabetes(2020)

OpenAlex related

10.2337/db20-1812-p