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Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6

Molecules(2025)10.3390/molecules30142919Source: DataRank Database

Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6 is a research paper published in Molecules (2025). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: goldTopics (19)IDs (PubMed, PMC)Annotations (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Zhousheng Xiao ORCID,Sunil Kumar Suman ORCID,Connor J. Cooper ORCID,Khanh Ha ORCID,James A. Carson ORCID

Live enrichment

PubMed:40733185 PMC:PMC12298599

United States National Institutes of Health (NIH)

Grant: R01-AR071930

United States National Institutes of Health (NIH)

Grant: R01-DK121132

United States National Institutes of Health (NIH)

Grant: FRS(160)/2021-2022/CHEMISTRY

NIDDK NIH HHS

Grant: R01 DK121132

NIAMS NIH HHS

Grant: R01 AR071930

goldLicense: cc-by

publisherhttps://www.mdpi.com/1420-3049/30/14/2919/pdf?version=1752146696

repositoryhttps://doaj.org/article/e85a208f142e4fce9757206da9558faa

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12298599

Europe_PMChttps://europepmc.org/articles/PMC12298599

Europe_PMChttps://europepmc.org/articles/PMC12298599?pdf=render

MeSH Terms

HumansReceptors, Interleukin-6Interleukin-6LigandsBinding SitesProtein BindingStructure-Activity RelationshipDrug DesignSTAT3 Transcription FactorSmall Molecule LibrariesMolecular Dynamics SimulationMolecular Docking SimulationInterleukin-6 Inhibitors

Keywords

InhibitorsBinding affinityMolecular dynamicshuman interleukin-6Ensemble DockingSmall Molecule Antagonist

Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6

FAIR Checklist

Authors (9)

Funding (5 grants)

Open Access

Topics

Annotations (Europe PMC)