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Combined Phytochemical Sulforaphane and Dietary Fiber Inulin Contribute to the Prevention of ER-Negative Breast Cancer via PI3K/AKT/MTOR Pathway and Modulating Gut Microbial Composition

Nutrients(2025)10.3390/nu17122023Source: DataRank Database

Combined Phytochemical Sulforaphane and Dietary Fiber Inulin Contribute to the Prevention of ER-Negative Breast Cancer via PI3K/AKT/MTOR Pathway and Modulating Gut Microbial Composition is a research paper published in Nutrients (2025). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 3.66)OA: goldTopics (77)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Brittany L. Witt,William J. Van Der Pol,Casey D. Morrow ORCID,Lennard W. Duck ORCID,Trygve O. Tollefsbol ORCID

Live enrichment

PubMed:40573134 PMC:PMC12196231 OpenAlex:https://openalex.org/W4411370033

National Institutes of Health

Grant: NCI R01CA178441

NCI NIH HHS

Grant: R01 CA178441

NCI NIH HHS

Grant: P30 CA013148

National Institutes of Health

Grant: 2R01CA178441-06A1

Combinatorial epigenetic-based prevention of breast cancer

FWCI

3.66

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/2072-6643/17/12/2023/pdf?version=1750166007

publisherhttps://www.mdpi.com/2072-6643/17/12/2023/pdf?version=1750166007

publisherhttps://www.mdpi.com/2072-6643/17/12/2023/pdf

journalhttps://doi.org/10.3390/nu17122023

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40573134

Fields of Study

Genomics, phytochemicals, and oxidative stressMicrobial Metabolites in Food BiotechnologyNutrition, Genetics, and Disease03 medical and health sciences0302 clinical medicineAnimalsIsothiocyanatesInulinSulfoxidesFemaleGastrointestinal MicrobiomeDietary FiberMiceTOR Serine-Threonine KinasesProto-Oncogene Proteins c-aktBreast NeoplasmsMice, TransgenicPhosphatidylinositol 3-KinasesSignal TransductionReceptors, EstrogenPhytochemicalsPrebioticsAnticarcinogenic Agents

MeSH Terms

Gastrointestinal MicrobiomeAnimalsBreast NeoplasmsDietary FiberFemaleInulinMice, TransgenicReceptors, EstrogenSulfoxidesSignal TransductionAnticarcinogenic AgentsIsothiocyanatesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktMicePrebioticsTOR Serine-Threonine KinasesPhytochemicals

Keywords

SulforaphaneEnterolactonePrebioticGut floraBiologyInulinPhytochemicalChemistryPharmacologyCancer researchBiochemistryEndocrinologyPhytoestrogensEstrogenBreast cancerTumor GrowthEpigenetic TherapyGut MicrobiomeDietary FiberPhytochemicalsBreast NeoplasmsMice, TransgenicArticleMicePhosphatidylinositol 3-KinasesIsothiocyanatesAnimalsAnticarcinogenic AgentsTOR Serine-Threonine KinasesGastrointestinal MicrobiomePrebioticsReceptors, EstrogenSulfoxidesFemaleProto-Oncogene Proteins c-aktSignal Transduction

Sustainable Development Goals

SDG 0: Good health and well-being