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Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Induced Neuropathy and Mitochondrial Toxicity: Limitations of the Poly-γ Hypothesis and the Potential Roles of Autophagy and Drug Transport

Pharmaceutics(2024)10.3390/pharmaceutics16121592Source: DataRank Database

Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Induced Neuropathy and Mitochondrial Toxicity: Limitations of the Poly-γ Hypothesis and the Potential Roles of Autophagy and Drug Transport is a research paper published in Pharmaceutics (2024). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 1.16)OA: goldTopics (31)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Arnav Joshi ORCID,Ross C. Larue ORCID,Eric D. Eisenmann ORCID,Rajgopal Govindarajan ORCID,John M. Haynes ORCID

Live enrichment

PubMed:39771570 PMC:PMC11677988 OpenAlex:https://openalex.org/W4405371022

National Institutes of Health

Grant: R01GM143217

National Institutes of Health

Grant: R01HL164443

NIH HHS

Grant: 5R01GM143217-04

Anti-HIV NRTIs and the lysosomal toxicity

NIH HHS

Grant: 1R01HL164443-01A1

Fundação para a Ciência e a Tecnologia, I.P.

Grant: PTDC/CCI-BIO/29266/2017

Deep Drug Discovery and Deployment

National Institutes of Health

Grant: 5R01HL164443-02

SLC29A3 lysosomal transporter in hematopoietic homeostasis and disease

FWCI

1.16

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/1999-4923/16/12/1592/pdf?version=1734094887

publisherhttps://www.mdpi.com/1999-4923/16/12/1592/pdf?version=1734094887

publisherhttps://www.mdpi.com/1999-4923/16/12/1592/pdf

journalhttps://doi.org/10.3390/pharmaceutics16121592

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39771570

Fields of Study

HIV Research and TreatmentHIV/AIDS drug development and treatmentHIV-related health complications and treatments0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Nucleoside Reverse Transcriptase InhibitorMedicineDidanosineAdverse effectPeripheral neuropathyReverse-transcriptase inhibitorDrugNeuropathic painNucleoside analogueIntensive care medicineAntiretroviral therapyHuman immunodeficiency virus (HIV)Mitochondrial toxicityPharmacologyNucleosideImmunologyViral loadBiologyAntiretroviral DrugsNrtiAntiretroviral Toxic NeuropathyHiv-Induced NeuropathyRS1-441Pharmacy and materia medicaReview

Sustainable Development Goals

SDG 0: Good health and well-being