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CD40 Agonist Overcomes T Cell Exhaustion Induced by Chronic Myeloid Cell IL-27 Production in a Pancreatic Cancer Preclinical Model

The Journal of Immunology(2021)10.4049/jimmunol.2000765Source: DataRank Database

CD40 Agonist Overcomes T Cell Exhaustion Induced by Chronic Myeloid Cell IL-27 Production in a Pancreatic Cancer Preclinical Model is a research paper published in The Journal of Immunology (2021). On theSindex it has a DataRank of 0. It has been cited 35 times.

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Open Access35 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)OA: bronzeTopics (64)IDs (PubMed, PMC)SDGs (1)

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Authors (9)

Meagan R. Rollins ORCID,Ellen J. Spartz ORCID,Taylor D. Mesojednik,Zoe C. Schmiechen ORCID,Jackson F. Raynor

Live enrichment

PubMed:33558374 PMC:PMC7977703

Pancreatic Cancer Action Network

Grant: 19-35-STRO

NIAID NIH HHS

Grant: T32 AI007313

NCI NIH HHS

Grant: R01 CA255039

NIAID NIH HHS

Grant: T35 AI118620

Pancreatic Cancer Action Network

Grant: 17-20-25-STRO

NCI NIH HHS

Grant: R01 CA249393

American Cancer Society

Grant: 124166-IRG-58-001-55-IRG65

National Institutes of Health

Grant: 5T35AI118620-04

Medical Student Summer Research Program in Infection and Immunity

American Association of Immunologists

bronzeLicense: OUP Standard Publication Reuse

https://doi.org/10.4049/jimmunol.2000765

https://europepmc.org/articles/pmc7977703?pdf=render

https://pubmed.ncbi.nlm.nih.gov/33558374

https://dx.doi.org/10.4049/jimmunol.2000765

Fields of Study

0301 basic medicine03 medical and health sciencesAnimalsAntineoplastic Agents, ImmunologicalB7-H1 AntigenCD40 AntigensCD8-Positive T-LymphocytesCarcinoma, Pancreatic DuctalDisease Models, AnimalDrug Screening Assays, AntitumorFemaleHumansInterleukinsLymphocyte ActivationLymphocytes, Tumor-InfiltratingMaleMiceMice, TransgenicMyeloid CellsPancreatic NeoplasmsPrimary Cell CultureTumor Cells, CulturedTumor Microenvironment

MeSH Terms

CD8-Positive T-LymphocytesLymphocytes, Tumor-InfiltratingTumor Cells, CulturedMyeloid CellsAnimalsMice, TransgenicHumansMiceCarcinoma, Pancreatic DuctalPancreatic NeoplasmsDisease Models, AnimalInterleukinsDrug Screening Assays, AntitumorLymphocyte ActivationFemaleMaleTumor MicroenvironmentPrimary Cell CultureAntineoplastic Agents, ImmunologicalCD40 AntigensB7-H1 Antigen

Keywords

MaleInterleukinsPrimary Cell CultureMice, TransgenicCD8-Positive T-LymphocytesLymphocyte ActivationB7-H1 AntigenPancreatic NeoplasmsDisease Models, AnimalMiceAntineoplastic Agents, ImmunologicalLymphocytes, Tumor-InfiltratingTumor Cells, CulturedAnimalsHumansFemaleMyeloid CellsCD40 AntigensDrug Screening Assays, AntitumorCarcinoma, Pancreatic Ductal

Sustainable Development Goals

SDG 3: 3. Good health