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ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling

The Journal of Immunology(2021)10.4049/jimmunol.2100742Source: DataRank Database

ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling is a research paper published in The Journal of Immunology (2021). On theSindex it has a DataRank of 0. It has been cited 25 times.

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Scored on demand from live citation data

Open Access25 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 1.17)OA: bronzeTopics (83)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Arunachalam Ramaiah ORCID,Gustavo Garcia ORCID,Spyridon Hasiakos ORCID,Vaithilingaraja Arumugaswami ORCID,Sonal Srikanth ORCID

Live enrichment

PubMed:34819389 PMC:PMC8702473 OpenAlex:https://openalex.org/W3215331148

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: AI146352

HHS | NIH | National Eye Institute

Grant: EY032149

NEI NIH HHS

Grant: R01 EY032149

NIDDK NIH HHS

Grant: R01 DK132735

NIAID NIH HHS

Grant: R01 AI146352

NIAID NIH HHS

Grant: R21 AI130653

NIDCR NIH HHS

Grant: K12 DE027830

National Institutes of Health

Grant: 5R01AI146352-04

Regulation of the STING pathway under sterile conditions

FWCI

1.17

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

bronzeLicense: OUP Standard Publication Reuse

journalhttps://journals.aai.org/jimmunol/article-pdf/208/1/74/1486240/ji2100742.pdf

publisherhttps://journals.aai.org/jimmunol/article-pdf/208/1/74/1486240/ji2100742.pdf

publisherhttps://academic.oup.com/jimmunol/article-pdf/208/1/74/61189241/ji2100742.pdf

journalhttps://doi.org/10.4049/jimmunol.2100742

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34819389

Fields of Study

interferon and immune responsesInflammasome and immune disordersImmune Cell Function and Interaction0301 basic medicine03 medical and health sciences0303 health sciencesA549 CellsAngiotensin-Converting Enzyme 2COVID-19Calcium SignalingClustered Regularly Interspaced Short Palindromic RepeatsDisease ResistanceDisease SusceptibilityGene Expression ProfilingHEK293 CellsHumansInterferon Type ILungMEF2 Transcription FactorsNeoplasm ProteinsORAI1 ProteinRespiratory MucosaSARS-CoV-2Stromal Interaction Molecule 1Transcription Factor AP-1

MeSH Terms

Stromal Interaction Molecule 1ORAI1 ProteinA549 CellsAngiotensin-Converting Enzyme 2COVID-19SARS-CoV-2Disease SusceptibilityHumansInterferon Type ILungNeoplasm ProteinsTranscription Factor AP-1Calcium SignalingRespiratory MucosaGene Expression ProfilingHEK293 CellsDisease ResistanceClustered Regularly Interspaced Short Palindromic RepeatsMEF2 Transcription Factors

Keywords

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Virology2019-20 coronavirus outbreakTonic (physiology)BiologyMedicineNeuroscienceInternal medicineInfectious disease (medical specialty)570ORAI1 ProteinMedical PhysiologyImmunology612Respiratory Mucosa2.1 Biological and endogenous factorsHumansClustered Regularly Interspaced Short Palindromic RepeatsCalcium SignalingStromal Interaction Molecule 1LungDisease ResistanceBiomedical and Clinical SciencesMEF2 Transcription FactorsSARS-CoV-2Gene Expression ProfilingCOVID-19Biological SciencesNeoplasm ProteinsTranscription Factor AP-1Infectious DiseasesEmerging Infectious DiseasesHEK293 CellsA549 CellsBiochemistry and cell biologyInterferon Type IAngiotensin-Converting Enzyme 2Disease Susceptibility

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being