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Synthesis and Evaluation of 2,5-Substituted Pyrimidines as Small-Molecule Gankyrin Binders

Future Medicinal Chemistry(2024)10.4155/fmc-2023-0124Source: DataRank Database

Synthesis and Evaluation of 2,5-Substituted Pyrimidines as Small-Molecule Gankyrin Binders is a research paper published in Future Medicinal Chemistry (2024). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)Impact (FWCI 0.28)OA: greenTopics (25)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Emma I. Kane ORCID,Tejashri Chavan ORCID,Taylor M Laflamme,Ethan Suarez,Mimansa Goyal

Live enrichment

PubMed:38205637 PMC:PMC10853842 OpenAlex:https://openalex.org/W4390743096

National Institute of General Medical Sciences

Grant: R15GM126432

National Institute of General Medical Sciences

Grant: SC2GM139672

NIGMS NIH HHS

Grant: R15GM126432, SC2GM139672

FWCI

0.28

Citation Percentile

0.5%

Citation Trend

2025

green

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10853842/pdf/fmc-16-239.pdf

publisherhttps://www.tandfonline.com/doi/pdf/10.4155/fmc-2023-0124

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10853842

journalhttp://dx.doi.org/10.4155/fmc-2023-0124

Fields of Study

Autophagy in Disease and TherapyUbiquitin and proteasome pathwaysBiochemical and Molecular Research

MeSH Terms

HumansNeoplasmsTumor Suppressor Protein p53Cell Line, TumorProteasome Endopeptidase Complex

Keywords

ChemistrySmall moleculeCell growthCell cycleCell biologyCancer cellPyrimidineAnkyrin repeatCellBiochemistryCancerBiologyLung cancerBreast cancerTumor Suppressor ProteinsProtein–protein InteractionsGankyrin

Sustainable Development Goals

SDG 0: Good health and well-being

Synthesis and Evaluation of 2,5-Substituted Pyrimidines as Small-Molecule Gankyrin Binders

FAIR Checklist

Authors (9)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)