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Thioredoxin interacting protein (TXNIP), a redox regulator, mediates the EPAC-RAP1 signaling dependency of primary melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.29.696903Source: DataRank Database

Thioredoxin interacting protein (TXNIP), a redox regulator, mediates the EPAC-RAP1 signaling dependency of primary melanoma is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)OA: greenTopics (12)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Mithalesh Kumar Singh ORCID,Sarah Altameemi ORCID,Sonia Gude,Sushmita Roy ORCID,Ryan Rossman

Live enrichment

PubMed:41509454 OpenAlex:https://openalex.org/W7117563831

United States Department of Veterans Affairs

Grant: I01BX004921

United States Department of Veterans Affairs

Grant: 1IK6BX006317

United States Department of Veterans Affairs

Grant: IK6BX006041

United States Department of Veterans Affairs

Grant: 1I01CX002393

United States Department of Veterans Affairs

Grant: I01CX002210

National Institutes of Health

Grant: R01CA261937

University of WisconsinMadison

Grant: Dr. Frederic E. Mohs Skin Cancer Research Chair endowment

University of WisconsinMadison

Grant: Evan P. and Marion Helafer Professorship

United States Department of Veterans Affairs

Grant: I01BX005917

BLRD VA

Grant: IK6 BX006317

green

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/12/29/2025.12.29.696903.full.pdf

repositoryhttps://doi.org/10.64898/2025.12.29.696903

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41509454

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12776316/

Fields of Study

Redox biology and oxidative stressCancer, Hypoxia, and Metabolismmelanin and skin pigmentation

Keywords

MelanomaTXNIPEffectorRegulatorActivator (genetics)Signal transductionCell growthPTENCancer cell