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TGF-β causes Docetaxel resistance in Prostate Cancer via the induction of Bcl-2 by acetylated KLF5 and Protein Stabilization

Theranostics(2020)10.7150/thno.44567Source: DataRank Database

TGF-β causes Docetaxel resistance in Prostate Cancer via the induction of Bcl-2 by acetylated KLF5 and Protein Stabilization is a research paper published in Theranostics (2020). On theSindex it has a DataRank of 0. It has been cited 65 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access65 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 2.83)OA: goldTopics (85)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Baotong Zhang ORCID,Lingwei Xiang,Siyuan Xia ORCID,Ömer Küçük ORCID,Xingming Deng ORCID

Live enrichment

PubMed:32685011 OpenAlex:https://openalex.org/W3038632268

National Institutes of Health

Grant: 5P30CA138292-11

Winship Cancer Institute Cancer Center Support Grant

NCI NIH HHS

Grant: P30 CA138292

FWCI

2.83

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.thno.org/v10p7656.pdf

publisherhttps://www.thno.org/v10p7656.pdf

publisherhttps://www.thno.org/v10p7656.htm

journalhttps://doi.org/10.7150/thno.44567

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32685011

Fields of Study

Kruppel-like factors researchCancer-related gene regulationTGF-β signaling in diseases0301 basic medicine03 medical and health sciencesAcetylationAnimalsApoptosisCell Line, TumorDocetaxelDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticGene Knockout TechniquesHEK293 CellsHumansKruppel-Like Transcription FactorsMaleMiceProstatic NeoplasmsProteasome Endopeptidase ComplexProtein StabilityProteolysisProto-Oncogene Proteins c-bcl-2Recombinant ProteinsTranscriptional ActivationTransforming Growth Factor beta1UbiquitinationXenograft Model Antitumor Assays

MeSH Terms

DocetaxelAcetylationAnimalsHumansMaleProstatic NeoplasmsRecombinant ProteinsTranscriptional ActivationGene Expression Regulation, NeoplasticApoptosisDrug Resistance, NeoplasmProto-Oncogene Proteins c-bcl-2Xenograft Model Antitumor AssaysCell Line, TumorProteasome Endopeptidase ComplexMiceKruppel-Like Transcription FactorsTransforming Growth Factor beta1UbiquitinationProtein StabilityGene Knockout TechniquesHEK293 CellsProteolysis

Keywords

Prostate cancerDocetaxelCancer researchCarcinogenesisCancerCancer cellChemistryBiologyMedicineInternal medicineMaleTranscriptional ActivationProteasome Endopeptidase ComplexProtein StabilityKruppel-Like Transcription FactorsProstatic NeoplasmsAcetylationApoptosisRecombinant ProteinsGene Expression Regulation, NeoplasticGene Knockout TechniquesMiceHEK293 CellsProto-Oncogene Proteins c-bcl-2Drug Resistance, NeoplasmCell Line, TumorProteolysisAnimalsHumansResearch PaperBcl-2 degradationKLF5 acetylationTGF-βdocetaxel resistance

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being