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Discovery of Small Molecule Bak Activator for Lung Cancer Therapy

Theranostics(2021)10.7150/thno.60349Source: DataRank Database

Discovery of Small Molecule Bak Activator for Lung Cancer Therapy is a research paper published in Theranostics (2021). On theSindex it has a DataRank of 0. It has been cited 34 times.

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Open Access34 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)OA: goldTopics (43)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Abu Syed Md Anisuzzaman,Andrew T. Magis ORCID,Guo Chen ORCID,Maohua Xie ORCID,Guojing Zhang ORCID

Live enrichment

PubMed:34373755 PMC:PMC8344021

NCI NIH HHS

Grant: R01 CA200905

NCI NIH HHS

Grant: R01 CA136534

NCI NIH HHS

Grant: P30 CA138292

NCI NIH HHS

Grant: P50 CA217691

NCI NIH HHS

Grant: R01 CA255257

National Institutes of Health

Grant: 5R01CA255257-03

Modulation of Mcl-1 for Treatment of Lung Cancer

National Institutes of Health

Grant: 5R01CA200905-03

Modulation of BAK in Lung Cancer Therapeutics

National Institutes of Health

Grant: 1P50CA217691-01A1

Emory University Lung Cancer SPORE

National Institutes of Health

Grant: 5R01CA136534-09

Structure-based anti-cancer drug development

goldLicense: CC BY NC

publisherhttps://www.thno.org/v11p8500.htm

Europe_PMChttps://europepmc.org/articles/PMC8344021

Europe_PMChttps://europepmc.org/articles/PMC8344021?pdf=render

https://doi.org/10.7150/thno.60349

https://pubmed.ncbi.nlm.nih.gov/34373755

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

MitochondriaAnimalsHumansMiceMice, NudeCarcinoma, Non-Small-Cell LungLung NeoplasmsPeptide FragmentsProto-Oncogene ProteinsProto-Oncogene Proteins c-bcl-2Antineoplastic AgentsXenograft Model Antitumor AssaysApoptosisProtein Bindingbcl-2 Homologous Antagonist-Killer ProteinSmall Molecule LibrariesProtein Domains

Keywords

ApoptosisLung cancerTherapybakBh3 DomainSmall Molecule ActivatorLung NeoplasmsMice, NudeAntineoplastic AgentsXenograft Model Antitumor AssaysPeptide FragmentsMitochondriaSmall Molecule LibrariesMicebcl-2 Homologous Antagonist-Killer ProteinProtein DomainsProto-Oncogene Proteins c-bcl-2Carcinoma, Non-Small-Cell LungProto-Oncogene ProteinsAnimalsHumansResearch PaperProtein Binding

Sustainable Development Goals

SDG 3: 3. Good health