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HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity

Theranostics(2021)10.7150/thno.67410Source: DataRank Database

HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity is a research paper published in Theranostics (2021). On theSindex it has a DataRank of 0. It has been cited 47 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access47 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)OA: goldTopics (39)IDs (PubMed, PMC)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Rajasekaran Mahalingam ORCID,Anand Kumar Singh ORCID,Shruti Dharmaraj ORCID,Taylor T. Chrisikos ORCID,Nabila Boukelmoune ORCID

Live enrichment

PubMed:34976203 PMC:PMC8692908

NCI NIH HHS

Grant: R01 CA230512

NINDS NIH HHS

Grant: R01 NS073939

NCI NIH HHS

Grant: R01 CA208371

NCI NIH HHS

Grant: P30 CA016672

NCI NIH HHS

Grant: R01 CA227064

National Institutes of Health

Grant: 5R01CA227064-05

PQ12 Targeting HDAC6 for Chemotherapy-Induced Neuropathy and Chemobrain

National Institutes of Health

Grant: 3P30CA016672-41S4

Cancer Center Support (CORE) Grant

National Institutes of Health

Grant: 5R01CA208371-05

Mesenchymal Stem Cells to Repair Chemobrain

goldLicense: cc-by

publisherhttps://www.thno.org/v12p0603.pdf

publisherhttps://www.thno.org/v12p0603.htm

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8692908

Europe_PMChttps://europepmc.org/articles/PMC8692908

Europe_PMChttps://europepmc.org/articles/PMC8692908?pdf=render

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

HippocampusMicrogliaSynapsesMitochondriaAnimalsMice, Inbred C57BLMicePyridazinesDoxorubicinTranscription, GeneticHomeostasisDose-Response Relationship, DrugFemaleCognitive DysfunctionHistone Deacetylase 6Disks Large Homolog 4 Protein

Keywords

MicrogliaChemobrainChemotherapy-induced Cognitive DysfunctionHdac6 InhibitionSingle-nucleus Rna SequencingDose-Response Relationship, DrugTranscription, GeneticHistone Deacetylase 6HippocampusMitochondriaMice, Inbred C57BLPyridazinesMiceDoxorubicinSynapsesAnimalsHomeostasisCognitive DysfunctionFemaleDisks Large Homolog 4 ProteinResearch Paper

Sustainable Development Goals

SDG 3: 3. Good health