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Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

eLife(2025)10.7554/elife.106814Source: DataRank Database

Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility is a research paper published in eLife (2025). On theSindex it has a DataRank of 0.

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geo gen uniprot doi

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Repositories this paper deposited data in (declared in PubMed).

GEOGSE164698 GSE292392

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Enrichment:Funding (16 grants)OA: goldTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (4)

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Authors (19)

Vadim Zhernovkov ORCID,Prasanna Babu Araveti ORCID,Suruchi Lata ORCID,Oleksii S. Rukhlenko ORCID,Salam Al Abdullatif

Live enrichment

PubMed:41037321 PMC:PMC12490860 OpenAlex:https://openalex.org/W4413821409

National Heart Lung and Blood Institute

Grant: R01HL126066

National Heart Lung and Blood Institute

Grant: R01HL133190

National Cancer Institute

Grant: R01CA244660

Horizon Europe

Grant: 10.3030/101136926

National Institute of General Medical Sciences

Grant: R01GM114864

National Institute on Aging

Grant: R01-AG052465

National Institute of General Medical Sciences

Grant: R01-GM135215

National Library of Medicine

Grant: R01LM013154

National Institute of General Medical Sciences

Grant: R01: 5R01GM127430-07

Health Research Board, Ireland

Grant: ERATRANSCAN-2022-001

Health Research Board, Ireland

Grant: EPPerMed-2024-1

Boston University

Grant: S10OD030269

Boston University

Grant: S10OD026983

NIGMS NIH HHS

Grant: R01 GM135215

NIA NIH HHS

Grant: R01 AG052465

NIGMS NIH HHS

Grant: R01 GM127430

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.106814

publisherhttps://doi.org/10.7554/elife.106814

publisherhttps://cdn.elifesciences.org/articles/106814/elife-106814-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/106814/elife-106814-v1.xml

publisherhttps://elifesciences.org/articles/106814

Fields of Study

interferon and immune responsesComputational Drug Discovery MethodsCytokine Signaling Pathways and InteractionsAnimalsMacrophage ActivationMiceHumansMycobacterium tuberculosisLipid PeroxidationInterferon Type IMacrophagesDisease Models, AnimalGranulomaTuberculosisTuberculosis, PulmonaryDisease SusceptibilityMice, Inbred C57BL

MeSH Terms

AnimalsDisease Models, AnimalDisease SusceptibilityGranulomaHumansInterferon Type IMacrophage ActivationMacrophagesMice, Inbred C57BLMycobacterium tuberculosisTuberculosisTuberculosis, PulmonaryLipid PeroxidationMice

Keywords

MacrophageLipid peroxidationImmunologyTuberculosisInterferonInterferon gammaCoupling (piping)ChemistryMicrobiologyMedicineBiologyBiochemistryCytokineOxidative stressIn vitroMaterials sciencePathologyMouseInfectious diseaseInflammationMYCType I interferonantioxidant defense

Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

FAIR Checklist

Authors (19)

Funding (16 grants)

Open Access

Topics

Annotations (Europe PMC)