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Exploration of precision coregulator TR-FRET identifies diverse signatures for LXR ligands relevant to discovery of nonlipogenic ABCA1 inducers

eLife(2025)10.7554/elife.109146Source: DataRank Database

Exploration of precision coregulator TR-FRET identifies diverse signatures for LXR ligands relevant to discovery of nonlipogenic ABCA1 inducers is a research paper published in eLife (2025). On theSindex it has a DataRank of 0.

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Repositories this paper deposited data in (declared in PubMed).

Dryad10.5061/dryad.hhmgqnkxc

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Enrichment:Funding (2 grants)OA: goldTopics (23)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Martha Ackerman-Berrier,Fahmida Alam ORCID,Sarah Turner,Velma Ganga Reddy ORCID,Christopher Penton

Live enrichment

PubMed:42325211 PMC:PMC13286573 OpenAlex:https://openalex.org/W4416666178

National Institutes of Health

Grant: T32GM008804

National Institutes of Health

Grant: U01AG076450

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.109146

publisherhttps://doi.org/10.7554/elife.109146

publisherhttps://cdn.elifesciences.org/articles/109146/elife-109146-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/109146/elife-109146-v1.xml

publisherhttps://elifesciences.org/articles/109146

Fields of Study

Cholesterol and Lipid MetabolismFatty Acid Research and HealthDrug Transport and Resistance Mechanisms

MeSH Terms

Liver X ReceptorsHumansLigandsFluorescence Resonance Energy TransferATP Binding Cassette Transporter 1

Keywords

CoactivatorLiver X receptorCorepressorAgonistNuclear receptorNuclear receptor coactivator 2Nuclear receptor coactivator 1Gene isoformBiochemistryLXRLipogenesisNoneChemical BiologyAtp-binding Cassette-a1Coregulator Selectivity

Exploration of precision coregulator TR-FRET identifies diverse signatures for LXR ligands relevant to discovery of nonlipogenic ABCA1 inducers

FAIR Checklist

Authors (13)

Funding (2 grants)

Open Access

Topics

Annotations (Europe PMC)