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Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

eLife(2020)10.7554/elife.51015Source: DataRank Database

Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance is a research paper published in eLife (2020). On theSindex it has a DataRank of 0. It has been cited 186 times.

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Open Access186 citations

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Enrichment:Funding (19 grants)OA: goldTopics (51)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Authors (16)

Horace Cox ORCID,Angela M. Early ORCID,Sachel Mok ORCID,Yassamine Lazrek ORCID,Jeanne-Céleste Paquet ORCID

Live enrichment

PubMed:32394893 PMC:PMC7217694

European Commission

Grant: Synergie GY0012082

Sante Publique France

Grant: NRC for malaria

Agence Nationale de la Recherche

Grant: ANR-10-LABX-25-01

Human Frontier Science Program

Grant: Long-Term Fellowship

Bill and Melinda Gates Foundation

Grant: OPP1201387

National Institutes of Health

Grant: R01 AI109023

National Institute of Allergy and Infectious Diseases

Grant: U19AI110818

World Health Organization

Grant: Global Malaria Program

National Institutes of Health

Grant: R01 124678

National Institutes of Health

Grant: R37 AI50234

U.S. Department of Defense

Grant: W81XWH1910086

World Health Organization

Grant: 001

NIAID NIH HHS

Grant: R01 AI124678

European Commission

Grant: GY0012082

NIAID NIH HHS

Grant: R37 AI050234

National Institutes of Health

Grant: 1R01AI109023-01A1

Defining P. falciparum resistance to artemisinin-based combination therapies

National Institutes of Health

Grant: 5R01AI124678-04

Elucidating the molecular basis of piperaquine resistance and the role of altered hemoglobin metabolism in Plasmodium falciparum

National Institutes of Health

Grant: 5R37AI050234-17

Defining the Role of PfCRT and PfMDR1 as Pleiotropic Mediators of Plasmodium falciparum Multidrug Resistance

National Institutes of Health

Grant: 2U19AI110818-06

Advancing Genomic Technologies to Combat Infectious Disease: Mapping Dynamics within Single Cells, Individual Hosts, and Global Populations

goldLicense: cc-by

publisherhttps://doi.org/10.7554/elife.51015

publisherhttps://cdn.elifesciences.org/articles/51015/elife-51015-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/51015/elife-51015-v1.xml

publisherhttps://elifesciences.org/articles/51015

repositoryhttps://doaj.org/article/c827568158c04d0c8f054f163d27f21d

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansPlasmodium falciparumMalaria, FalciparumArtemisininsProtozoan ProteinsAntimalarialsDrug ResistanceHaplotypesMutationGenes, ProtozoanGuyanaGenetic FitnessWhole Genome Sequencing

Keywords

EvolutionMalariaMicrobiologyInfectious diseaseepidemiologySouth AmericaGuyanaGlobal HealthP. FalciparumArtemisinin ResistanceKelch 13QH301-705.5ScienceGenes, ProtozoanPlasmodium falciparumDrug ResistanceProtozoan Proteins[SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biologyAntimalarialsHumansBiology (General)Malaria, FalciparumWhole Genome SequencingQRArtemisininsEpidemiology and Global HealthHaplotypes[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieMutation[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases[SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]MedicineGenetic Fitness[SDV.MP.PAR] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology

Sustainable Development Goals

SDG 3: 3. Good health

Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

FAIR Checklist

Authors (16)

Funding (19 grants)

Open Access

Topics

Annotations (Europe PMC)