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Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α

eLife(2020)10.7554/elife.52668Source: DataRank Database

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α is a research paper published in eLife (2020). On theSindex it has a DataRank of 0. It has been cited 130 times.

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Open Access130 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (22 grants)OA: goldTopics (66)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Authors (19)

Magdalena K. Bielecka ORCID,Paul Ogongo ORCID,Naomi F. Walker ORCID,Matthew J. Ellis ORCID,Diana J. Garay‐Baquero ORCID

Live enrichment

PubMed:32091388 PMC:PMC7058383

Medical Research Council

Grant: MR/P023754/1

Bioengineering to combat the tuberculosis pandemic

Medical Research Council

Grant: MR/N006631/1

Investigating multi-drug resistant tuberculosis in the 3-dimensional bioelectrospray cell culture model

Wessex Medical Research

Grant: Innovation Grant 2017

Wellcome Trust

Grant: 210662/Z/18/Z

Bill and Melinda Gates Foundation

Grant: OPP1137006

Cancer Research UK

Grant: 23562

Medical Research Council

Grant: MR/S024220/1

MICA Investigating CD1c lipid-antigen presentation and its role in tuberculosis

Wellcome Trust

Grant: FC0010218

Wellcome Trust

Grant: 203135

Centre for Infectious Diseases Research in Africa (CIDRI-Africa)

Wellcome Trust

Grant: 104803

Host directed therapies against tuberculosis.

National Institutes of Health

Grant: U19AI111276

National Institute for Health Research

Grant: Academic Clinical Lectureship

National Centre for the Replacement, Refinement and Reduction of Animals in Research

Grant: NC/L001039/1

National Institute for Health Research (NIHR)

Grant: CL-2015-20-001

The Francis Crick Institute

Grant: 10218

Wessex Medical Research

Grant: 2017

Wellcome Trust

Grant: 104803/Z/14/Z

Rosetrees

Grant: M540

Wellcome Trust

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5U19AI111276-07

Biomarkers and Mechanisms of Paucibacillary and Latent Tuberculosis

National Institutes of Health

Grant: 5U19AI111276-02

Biomarkers and Mechanisms of Paucibacillary and Latent Tuberculosis

Wellcome Trust

Grant: 210662

Investigating the role of lung Tissue resident memory T-cell in the immunopathology of human TB

goldLicense: CC BY

publisherhttps://cdn.elifesciences.org/articles/52668/elife-52668-v2.pdf

publisherhttps://cdn.elifesciences.org/articles/52668/elife-52668-v2.xml

publisherhttps://elifesciences.org/articles/52668

Europe_PMChttps://europepmc.org/articles/PMC7058383

Europe_PMChttps://europepmc.org/articles/PMC7058383?pdf=render

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansMycobacterium tuberculosisGranulomaTumor Necrosis Factor-alphaImmunotherapyMicrospheresCell HypoxiaUp-RegulationLatent TuberculosisProgrammed Cell Death 1 Receptor

Keywords

HumanTuberculosisPathologyTNFInflammationimmunologyHost-pathogen InteractionImmune Checkpoint InhibitorsLife Sciences & Biomedicine - Other TopicsCD4-Positive T-LymphocytesProgrammed Cell Death 1 ReceptorHYPOXIACD8-Positive T-Lymphocytes0601 Biochemistry and Cell Biologywc_302Immunology and InflammationINFECTIONMEDIATES RESISTANCEBiology (General)Human Biology & PhysiologyGranulomaQRCell HypoxiaMicrospheresUp-RegulationGROWTHMedicineMYCOBACTERIUM-TUBERCULOSISwf_200ImmunotherapyLife Sciences & BiomedicineModel organisms570QH301-705.5Science610Infectious DiseaseHOST-DIRECTED THERAPIESLatent TuberculosisHumansBiologyScience & TechnologyTumor Necrosis Factor-alphaFOS: Clinical medicineNECROSIS-FACTOR-ALPHAMycobacterium tuberculosisTISSUELATENTwf_140MACROPHAGE

Sustainable Development Goals

SDG 3: 3. Good health