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The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans

eLife(2020)10.7554/elife.56205Source: DataRank Database

The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans is a research paper published in eLife (2020). On theSindex it has a DataRank of 1.5. It has been cited 73 times, with 44 citing works in its 1-hop citation network.

N/A

1.5DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access73 citations · 44 citing works in its network

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Linked data & code

geo doi

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE143618

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 2.09)OA: goldTopics (48)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 42%Citation Network 58%

Base Score Contribution

0.646

From this paper's citation signal

Citation Network Contribution

0.881

From 38 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 44 citers.

Combining Bulk RNA-seq and scRNA-seq data to identify RNA m5C methyltransferases NSUN1: a rising star as a biomarker for cancer diagnosis, prognosis and therapy
Translational Cancer Research202310 citations24 referencesContributes 0.100
A Cross-Tissue Investigation of Molecular Targets and Physiological Functions of Nsun6 Using Knockout Mice
International Journal of Molecular Sciences202214 citations30 referencesContributes 0.090
RNA 5-methylcytosine regulates YBX2-dependent liquid-liquid phase separation
Fundamental Research202136 citations47 referencesContributes 0.077
RNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer
Experimental & Molecular Medicine202459 citations62 referencesContributes 0.066
Exploring the role of ribosomal RNA modifications in cancer
Current Opinion in Genetics & Development202418 citations66 referencesContributes 0.045

Authors (13)

Jarod Rollins ORCID,Teresa L. Krammer ORCID,Fabian Nagelreiter ORCID,Isabella Stocker,Ludivine Wacheul ORCID

Live enrichment

PubMed:33289480 PMC:PMC7746234 OpenAlex:https://openalex.org/W3111994907

Austrian Science Fund

Grant: P30623

Nsun5 in ribosome function and mammalian healthy lifespan

Hochschuljubiläumsstiftung der Stadt Wien

Grant: H- 327123/2018

Austrian Science Fund

Grant: I2514

The role of specialized ribosomes in stress resistance and healthy aging

National Institute of General Medical Sciences

Grant: P20GM103423

Mount Desert Island Biological Laboratory

Grant: James L. Boyer Fellowship

National Institute of General Medical Sciences

Grant: P20GM104318

Belgian National Fund for Scientific Research

Grant: F.R.S./FNRS

Région Wallonne

Grant: grant RIBO cancer no. 1810070

Austrian Science Fund

Grant: W1224

Biomolecular Technology of Proteins - BioToP

Région Wallonne (DGO6)

Grant: 1810070

NIH HHS

Grant: P40 OD010440

National Institutes of Health

Grant: 1P40OD010440-01

Caenorhabditis Genetics Center

National Institutes of Health

Grant: 5P20GM104318-05

Comparative Biology of Tissue Repair, Regeneration and Aging

National Institutes of Health

Grant: 5P20GM103423-20

Comparative Functional Genomics INBRE in Maine

Université Libre de Bruxelles

FWCI

2.09

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.56205

publisherhttps://doi.org/10.7554/elife.56205

publisherhttps://cdn.elifesciences.org/articles/56205/elife-56205-v2.pdf

publisherhttps://cdn.elifesciences.org/articles/56205/elife-56205-v2.xml

publisherhttps://elifesciences.org/articles/56205

Fields of Study

RNA modifications and cancerRNA Research and SplicingRNA regulation and disease0301 basic medicine03 medical and health sciences

MeSH Terms

AgingAnimalsFemaleFertilityLongevityMethyltransferasesOogenesisRNA Processing, Post-TranscriptionalCaenorhabditis elegansCaenorhabditis elegans Proteins

Keywords

Caenorhabditis elegansBiologyRibosome biogenesisRibosomal RNACell biologyGene knockdownRibosomeRNARNA interferenceGeneticsGeneAgingTranslationdevelopmental biologyC. ElegansRna MethylationNsun1/nop2/p120Nsun5/rcm1QH301-705.5ScienceLongevityOogenesisAnimalsBiology (General)RNA Processing, Post-TranscriptionalCaenorhabditis elegans ProteinsQRMethyltransferasesFertilityMedicineBiologie cellulaireFemale

Additional file 19 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 19 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 18 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 18 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 16 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 16 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 15 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 15 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 10 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 10 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 7 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 7 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 6 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 6 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 5 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 5 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 4 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 4 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 3 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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Additional file 3 of ADARs regulate cuticle collagen expression and promote survival to pathogen infection

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The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (13)

Funding (15 grants)

Impact

Open Access

Topics

Linked Datasets (25)

Annotations (Europe PMC)

Related Papers (10)