Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins

eLife(2020)10.7554/elife.57089Source: DataRank Database

Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins is a research paper published in eLife (2020). On theSindex it has a DataRank of 0. It has been cited 36 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access36 citations

Download PDF

Cite:

Linked data & code

pdb doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 5.29)OA: goldTopics (79)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (9)

Justin L Shumate ORCID,Jenna G Caldwell ORCID,Nadia Elghobashi‐Meinhardt ORCID,Albert Lu ORCID,Lichao Zhang ORCID

Live enrichment

PubMed:32410728 PMC:PMC7228765 OpenAlex:https://openalex.org/W3024366742

National Institutes of Health

Grant: 5R01HL134991-04

Cholesterol Regulation of Lysosomes

NHLBI NIH HHS

Grant: R01 HL134991

NCI NIH HHS

Grant: P30 CA124435

National Institutes of Health

Grant: 3P30CA124435-08S1

Stanford University Cancer Center

Chan Zuckerberg BioHub

Ara Parseghian Medical Research Foundation

FWCI

5.29

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.57089

publisherhttps://doi.org/10.7554/elife.57089

publisherhttps://cdn.elifesciences.org/articles/57089/elife-57089-v1.pdf

publisherhttps://cdn.elifesciences.org/articles/57089/elife-57089-v1.xml

publisherhttps://elifesciences.org/articles/57089

Fields of Study

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsAnticholesteremic AgentsBiological TransportCholesterolEzetimibeHEK293 CellsHeLa CellsHumansIntracellular Signaling Peptides and ProteinsLysosomesMembrane Transport ProteinsMolecular Dynamics SimulationNiemann-Pick C1 ProteinProtein DomainsSf9 CellsStructure-Activity Relationship

MeSH Terms

EzetimibeProtein DomainsNiemann-Pick C1 ProteinAnimalsAnticholesteremic AgentsBiological TransportCholesterolHeLa CellsHumansLysosomesStructure-Activity RelationshipMembrane Transport ProteinsIntracellular Signaling Peptides and ProteinsMolecular Dynamics SimulationHEK293 CellsSf9 CellsHela Cells

Keywords

NPC1Dynamics (music)CholesterolDomain (mathematical analysis)Cell biologyChemistryBiologyComputational biologyBiochemistryPhysicsMathematicsEndosomeHumanLysosomeCholesterol transportEzetimibeLdl CholesterolChemical BiologyNiemann Pick C DiseaseQH301-705.5ScienceMolecular Dynamics SimulationStructure-Activity RelationshipProtein DomainsBiochemistry and Chemical BiologyNiemann-Pick C1 ProteinSf9 CellsAnimalsHumansBiology (General)Anticholesteremic AgentsQRIntracellular Signaling Peptides and ProteinsMembrane Transport ProteinsBiological TransportHEK293 CellsMedicineLysosomesHeLa Cells

Sustainable Development Goals

SDG 3: 3. Good healthSDG 16: 16. Peace & justice

Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins

FAIR Checklist

Authors (9)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)