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DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

eLife(2021)10.7554/elife.58430Source: DataRank Database

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia is a research paper published in eLife (2021). On theSindex it has a DataRank of 2.8. It has been cited 144 times, with 100 citing works in its 1-hop citation network.

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2.8DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access144 citations · 100 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE147221 GSE80417 GSE84727

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (40 grants)Impact (FWCI 8.74)OA: goldTopics (94)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 27%Citation Network 73%

Base Score Contribution

0.747

From this paper's citation signal

Citation Network Contribution

2.0

From 90 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 100 citers.

Genome-wide discovery of circulating cell-free DNA methylation biomarkers for colorectal cancer detection
Clinical Epigenetics202323 citations23 referencesContributes 0.138
Methylation Analysis in Monozygotic Twins With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine
Frontiers in Psychiatry202112 citations38 referencesContributes 0.067
A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples
Clinical Epigenetics202212 citations39 referencesContributes 0.066
Comprehensive evaluation of the implementation of episignatures for diagnosis of neurodevelopmental disorders (NDDs)
Human Genetics202312 citations43 referencesContributes 0.060
Dysmaturational Longitudinal Epigenetic Aging During Transition to Psychosis
Schizophrenia Bulletin Open202213 citations45 referencesContributes 0.059

Authors (46)

Emma Dempster ORCID,Georgina Mansell ORCID,Joe Burrage ORCID,Nick Bass,Marc M. Bohlken

Live enrichment

PubMed:33646943 PMC:PMC8009672 OpenAlex:https://openalex.org/W3134537818

Wellcome Trust

Grant: 075491/Z/04/B

Academy of Finland

Grant: 263278

Genomic epidemiology of addictions and their consequences - national, Nordic and international dimensions.

Medical Research Council

Grant: Fellowship (MR/M008436/1)

NIMH NIH HHS

Grant: R01 MH052857

Medical Research Council

Grant: Clinical Research Infrastructure Funding (MR/M008924/1)

Medical Research Council

Grant: MR/L010305/1

Dutch Research Council (NWO)

Grant: VIDI grant (number 91718336)

Finland Centre of Excellence in Complex Disease Genetics

Grant: 213506

CoE in Complex Disease Genetics

Karolinska Institutet

Grant: ALF 20090183

Medical Research Council

Grant: MR/K013807/1

Methylomic profiling in schizophrenia: towards an integrated genetic-epigenetic approach

Wellcome Trust

Grant: 090532/Z/09/Z

Academy of Finland

Grant: 312073

Center of Excellence in Complex Disease Genetics-from Discovery to Precision Medicine / Consortium: CoECDG

Medical Research Council

Grant: G0800509

Molecular Genetics of Schizophrenia

Medical Research Council

Grant: G0801418

The Centre for Neuropsychiatric Genetics and Genomics

Medical Research Council

Grant: MR/M008436/1

Biological mechanisms underlying the onset and outcome of cannabis-associated psychosis.

Medical Research Council

Grant: MR/R005176/1

Regulatory genomic profiling in schizophrenia

National Institute for Health Research (NIHR)

Grant: RP-PG-0606-1049

Wellcome Trust

Grant: 072894/Z/03/Z

Medical Research Council

Grant: MR/T007818/1

National Institutes of Health

Grant: R01 MH52857

Wellcome Trust

Grant: 085475/B/08/Z

Wellcome Trust

Grant: 085475/Z/08/Z

Finland Centre of Excellence in Complex Disease Genetics

Grant: 129680

Center of Excellence in Complex Disease Genetics

European Union 7th Framework Programme

Grant: 279227

Pharmacogenomic biomarkers as clinical decision making tools for clozapine treatment of schizophrenia

Vetenskapsrådet

Grant: D0886501

Medical Research Council

Grant: MR/L011794/1

Academy of Finland

Grant: 265240

Genomic epidemiology of addictions and their consequences - national, Nordic and international dimensions

Karolinska Institutet

Grant: ALF 20100305

NIMH NIH HHS

Grant: R01 MH077139

Medical Research Council

Grant: MR/M008924/1

Accelerated discovery of functional non-coding genomic variation using single molecule real-time (SMRT) sequencing.

Swedish Research Council

Grant: unidentified

unidentified

Wellcome Trust

Grant: 085475

WTCCC2 core activities

Science Foundation Ireland

Grant: 08/IN.1/B1916

Genes to Biology: A Translational Pipeline for Schizophrenia

European Commission

Grant: 241909

European Network of National Schizophrenia Networks Studying Gene-Environment Interactions

National Institutes of Health

Grant: 5R01MH052857-14

Neural Phenotypes for Schizophrenia and Bipolar Disorder

Wellcome Trust

Grant: 090532

Understanding the genetic basis of common human diseases: core funding for the Wellcome Trust Centre for Human Genetics.

Wellcome Trust

Grant: 072894

Resource for psychoses genomics, Ireland (RPGI).

Wellcome Trust

Grant: 075491

Identification and functional analysis of susceptibility genes in multi- factorial diseases

National Institutes of Health

Grant: 5R01MH077139-05

1/2 A Large-Scale Schizophrenia Association Study in Sweden

Wellcome Trust

FWCI

8.74

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.7554/elife.58430

publisherhttps://doi.org/10.7554/elife.58430

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33646943

repositoryhttps://cris.maastrichtuniversity.nl/en/publications/e452989f-7ebb-418e-a9c2-3e58be83b568

repositoryhttp://www.scopus.com/inward/record.url?scp=85101932123&partnerID=8YFLogxK

Fields of Study

Epigenetics and DNA MethylationFamily Caregiving in Mental IllnessSchizophrenia research and treatment0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

EpigenomeSchizophrenia, Treatment-ResistantAdultAgedEnglandFemaleHumansIrelandMaleMiddle AgedPsychotic DisordersScotlandSwedenDNA MethylationYoung Adult

Keywords

PsychosisSchizophrenia (object-oriented programming)DNA methylationClozapineMethylationBiologyMedicineBioinformaticsGeneticsPsychiatryDNAGeneGene expressionHumanSchizophreniaGenomicsEpigeneticsMaleBLOODHIGH-POTENCY CANNABISHEALTH-F2-2010-241909DISEASEMedical Genetics and GenomicsMR/M008924/1EpigenomeWIDE ASSOCIATIONWellcome TrustBiology (General)RISKGeneral NeuroscienceQRRP-PG-0606-1049Middle AgedMedicinsk genetik och genomikTRAITEnglandR01 MH52857K013807HUMAN BRAIN-TISSUEFemaleBURDENMR/K013807/1Schizophrenia, Treatment-ResistantAdult330MR/R005176/1QH301-705.5ScienceGeneral Biochemistry,Genetics and Molecular BiologyMETHYLOMIC VARIATION610R Medicine075491/Z/04/BPsykiatriYoung AdultMR/M008436/1Humans1ST-EPISODE PSYCHOSISEuropean CommissionNational Institute for Health Research (NIHR)AgedSwedenGeneral Immunology and Microbiology279227Genetics and GenomicsMedical Research Council (MRC)Psychotic DisordersScotland072894/Z/03/Z090532/Z/09/ZOtherIreland

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being